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Current Opinion in Anaesthesiology, 2010 Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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Journal of PeriAnesthesia Nursing, 2007
Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing.
F, Yanagidate, G R, Strichartz
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Local anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. This chapter, on the analgesic aspects of local anesthetics, reviews their broad actions that affect many different molecular targets and disrupt their functions in pain processing.
F, Yanagidate, G R, Strichartz
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Dermatologic Surgery, 1996
Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
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Dermatology is dependent upon the effects of local anesthetics for diagnostic and therapeutic interventions. A working knowledge of the drugs' actions and interactions is necessary for anyone aspiring to optimize the benefits derived from the use of local anesthetic agents.This article reviews nerve physiology, pharmacology, classification of local ...
R A, Skidmore +2 more
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Annals of Emergency Medicine, 1985
Local anesthetics are remarkably useful agents that enhance patient comfort and improve patient compliance. Their use, however, requires an understanding of their action, proper dosages, potential risks, and treatment of reactions. We have presented the history, pharmacokinetics, action, risks of using, and ways in which agents are used to treat the ...
R S, Altman +2 more
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Local anesthetics are remarkably useful agents that enhance patient comfort and improve patient compliance. Their use, however, requires an understanding of their action, proper dosages, potential risks, and treatment of reactions. We have presented the history, pharmacokinetics, action, risks of using, and ways in which agents are used to treat the ...
R S, Altman +2 more
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Veterinary Clinics of North America: Large Animal Practice, 1981
Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals.Local anesthetics are ...
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Local anesthetics are used in a wide range of clinical situations to prevent acute pain and to stop or ameliorate pain produced by cancer or pain associated with chronic painful conditions. Knowledge of the pharmacology of local anesthetics is essential for their safe use and selection of specific agents to achieve intended goals.Local anesthetics are ...
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2014
The Side Effects of Drugs Annuals form a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of relevant publications from January 2012 to June 2013
Sekandarzad, Mir Wais, Schug, Stephan A.
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The Side Effects of Drugs Annuals form a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of relevant publications from January 2012 to June 2013
Sekandarzad, Mir Wais, Schug, Stephan A.
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Regional Anesthesia and Pain Medicine, 2004
Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang, Zink, Bernhard M, Graf
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Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang, Zink, Bernhard M, Graf
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The American Journal of Surgery, 1957
Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
J H, MITCHELL +2 more
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Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
J H, MITCHELL +2 more
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Emergency Medicine Clinics of North America, 1992
Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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The Pharmacology of Local Anesthetics
Veterinary Clinics of North America: Equine Practice, 1991Understanding of the pharmacology of local anesthesia is important for selection of a local anesthetic for use in equine standing surgery. In general, the action potential is inhibited by local anesthetics by preventing the influx of sodium ions across the axonal membrane.
T K, Day, R T, Skarda
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