Results 231 to 240 of about 4,751,276 (340)

Gradient Solvent Replacement‐Mediated Formation of High‐Strength Hydrogel‐Forming Microneedle for Long‐Term Drug Delivery

Advanced Science, EarlyView.
A high‐strength pH‐responsive hydrogel‐forming microneedle integrates gradient solvent replacement to enhance the mechanical properties of the acrylonitrile‐acrylic acid copolymer network, ensuring robust transdermal penetration and long‐term drug release.
Hui Li, Fengzhen Meng, Chengwei Hu, Zhiyun Wu, Liuzhi Hao, Caijun Sun, Lijing Fang, Fan Pan, Shaoquan Bian, Huipeng Li, Mingjun Li, Bo Liu, Xiaoli Zhao   +12 more
wiley   +1 more source

Sustained release local anesthetics for pain management: relevance and formulation approaches. [PDF]

Front Pain Res (Lausanne)
Getachew M, Tesfaye H, Yihunie W, Ayenew T, Alemu S, Dagnew EM, Biyazin Y, Abebe D, Degefu N, Abebaw A.   +9 more
europepmc   +1 more source

THE COMPARATIVE POTENCY OF RECENTLY INTRODUCED LOCAL ANESTHETIC AGENTS FOR INTRATHECAL USE

, 1963
Enoch Authement, M. AVERRETT, John Adriani   +2 more
openalex   +1 more source

Preventive Analgesia by Local Anesthetics: The Reduction of Postoperative Pain by Peripheral Nerve Blocks and Intravenous Drugs

Anesthesia and Analgesia, 2013
Antje M. Barreveld, J. Witte, H. Chahal, M. Durieux, G. Strichartz   +4 more
semanticscholar   +1 more source

Sleep Deprivation Aggravates Periodontitis Through Trigeminal‐Periodontal Neuroimmune Pathway Mediated by the AChE‐ACh‐α7nAChR Axis

Advanced Science, EarlyView.
Sleep deprivation (SD) exacerbates ligature‐induced periodontitis (LIP) through the trigeminal nerve‐periodontal neuroimmune pathway mediated by the acetylcholinesterase (AChE)‐acetylcholine (ACh)‐α7 nicotinic receptor (α7nAChR) axis. While electroacupuncture (EA) alleviates the condition of LIP combined with SD by activating the α7nAChR.
Kehao Liu, Qi Huang, Mingcong Yang, Ziyu Huang, Kamoran Tuerhong, Yue Zu, Ying Xie, Xuehui Hu, Qianyu Zhang, Ping He, Nannan Huang, Rong Zhang, Yuzhou Li, Sheng Yang   +13 more
wiley   +1 more source

Local anesthetics as a tool for Staphylococcus spp. control: a systematic review. [PDF]

Braz J Microbiol
Barreto Bellusci H, Gervasoni LF, Peixoto IC, De Oliveira LB, de Oliveira Vieira KC, Toledo ACCG, de Oliveira CBS, Mareco EA, Naga RM, Cataneli VP, Nai GA, Winkelströter LK.   +11 more
europepmc   +1 more source

Experimental Study on Some Dental Local Anesthetics with Reference to Antagonistic Actions to Histamine, Acetylcholine, Nicotine, Epinephrine and Barium Chloride

, 1961
Yoshio Sugiyama, Masafumi Kobayashi, Toyoyuki Tamura   +2 more
openalex   +2 more sources

Targeting GPX4 to Induce Ferroptosis Overcomes Chemoresistance Mediated by the PAX8‐AS1/GPX4 Axis in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
PAX8‐AS1 drives chemoresistance in intrahepatic cholangiocarcinoma by activating NRF2‐mediated GPX4 transcription and stabilizing GPX4 mRNA via IGF2BP3. Targeting the PAX8‐AS1/GPX4 axis with a GPX4 inhibitor enhances the efficacy of gemcitabine and cisplatin in preclinical models, offering a promising strategy to overcome chemotherapy resistance in ...
Zhi‐Wen Chen, Ji‐Jun Shan, Mo Chen, Zong Wu, Yi‐Ming Zhao, Hong‐Xu Zhu, Xin Jin, Yi‐Xiu Wang, Yi‐Bin Wu, Zhen Xiang, Zhi‐Wen Ding, Zhen‐Hai Lin, Long‐Rong Wang, Lu Wang   +13 more
wiley   +1 more source

The efficacy of wound catheter infusion with local anesthetics for the treatment of postoperative pain in children: A systematic review. [PDF]

Paediatr Neonatal Pain
Swenker DJ, Dirckx M, Staals LM.
europepmc   +1 more source

Dual‐Biomimetic Bone Adhesive with Osteoimmunomodulatory Capabilities for Anatomical Reconstruction of Comminuted Fractures

Advanced Science, EarlyView.
A structurally and functionally dual bionic bone adhesive is engineered through an organic–inorganic cohesion strategy, which significantly reinforces the adhesive's bone tissue adhesion as well as osteogenic activity. In a pioneering rabbit radius comminuted fracture model, the bone adhesive exhibits exceptional capability in immobilizing bone ...
Junyao Cheng, Hufei Wang, Ming Li, Jianpeng Gao, Xiao Liu, Chuyue Zhang, Pengfei Chi, Bo Li, Yuan Xve, Daoyang Fan, Zheng Wang, Jianheng Liu, Xing Wang, Licheng Zhang   +13 more
wiley   +1 more source