Results 271 to 280 of about 4,888,294 (346)

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source

Effect of Dental Local Anesthetics on Reactive Oxygen Species: An In Vitro Study. [PDF]

Cureus
Kuroda H, Tsukimoto S, Kosai A, Komatsu N, Ouchi T, Kimura M, Sato-Boku A, Yoshida A, Yoshino F, Abe T, Shibukawa Y, Sanuki T.   +11 more
europepmc   +1 more source

Femoral nerve blockade using various concentrations of local anesthetic for knee arthroscopy in the pediatric population

, 2016
Giorgio Veneziano, Jennifer Tripi, Dmitry Tumin, Mumin Hakim, David P. Martin, Ralph J. Beltran, Kevin E. Klingele, Tarun Bhalla, Joseph D. Tobias   +8 more
openalex   +2 more sources

Long‐Term Memory Updating Parallels Altered Awake and Sleep Hippocampal Replays

Advanced Science, EarlyView.
This study introduces a behavioral paradigm for memory updating and reveals underlying hippocampal mechanisms. Replays of place cells predict future behavioral choices during behavior and show a bias toward high‐reward locations during non‐rapid eye movement (NREM) sleep, specifically within the memory updating process.
Jifu Tong, Yuanwei Xing, Yawen Zheng, Linshu Wang, Shan Shao, Jiao Wu, Longyu Ma, Shuting Liu, Naizheng Liu, Xuetao Qi, Ting Wang, Kun Cui, Shuang Cui, You Wan, Ming Yi   +14 more
wiley   +1 more source

A Clinical Comparative Study of Dexmedetomidine, Dexamethasone, and Clonidine as Adjuvants to Local Anesthetics in Supraclavicular Brachial Plexus Blocks. [PDF]

Cureus
Yadav UP, Agrawal J, Singh A, Goyal P.
europepmc   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

Advanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan, Yinghao Hong, Xiangjun Ji, Jing Xiang, Jinxi Liu, Lixin Liang, Meng Ren, Wenhan Chen, Tengfei Xu, Zhijie Li, Tieliu Shi, Yong Jiang, Huaping Liang, Jinghua Liu   +13 more
wiley   +1 more source

Drug-Dependent Inhibitory Effects on Corneal Epithelium Structure, Cell Viability, and Corneal Wound Healing by Local Anesthetics. [PDF]

Int J Mol Sci
Foja S, Heinzelmann J, Hünniger S, Viestenz A, Rüger C, Viestenz A.   +5 more
europepmc   +1 more source

Regular versus Irregular Exercise Differentially Modulates Hippocampal‐Hepatic Acetylcholine Flux to Coordinate Fear Memory Extinction and Liver Inflammation

Advanced Science, EarlyView.
Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma, Kuan Zhang, Long Yi, Chuanyan Yang, Hedong Lang, Jianbin Sun, Jin Li, Qian Bai, Yuhang He, Shuang‐Shuang Dai, Man‐Tian Mi   +10 more
wiley   +1 more source

Use of lipid emulsion therapy in local anesthetic overdose

, 2017
Özgür Karcıoğlu
openalex   +2 more sources

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

Advanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang, Wei Zhou, Marcelo Cypel, Todd L. Demmy, Gal Shafirstein, Guillermo Garza, Emily Gawrys, Joanna Bogusiewicz, Barbara Bojko, Janusz Pawliszyn   +9 more
wiley   +1 more source