Results 281 to 290 of about 4,751,276 (340)
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Regional Anesthesia and Pain Medicine, 2004
Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang Zink, Bernhard M. Graf
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Skeletal muscle toxicity is a rare and uncommon side effect of local anesthetic drugs. Intramuscular injections of these agents regularly result in reversible myonecrosis. The extent of muscle damage is dose dependent and worsens with serial or continuous administration. All local anesthetic agents that have been examined are myotoxic, whereby procaine
Wolfgang Zink, Bernhard M. Graf
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The American Journal of Surgery, 1957
Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
John H. Mitchell +2 more
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Abstract 1. 1. An outline of the pharmacology of propoxycaine HCI, a new local anesthetic, is presented. 2. 2. Seventy-one cases in which propoxycaine HCI was used as a local anesthetic are reviewed. 3. 3. Salient features of the satisfactory performance of propoxycaine HCI include: (a) rapid onset, (b) effective in small dosage, (c ...
John H. Mitchell +2 more
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Emergency Medicine Clinics of North America, 1992
Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Emergency physicians often rely on the use of local anesthetic agents to relieve patient discomfort, and research continues in an effort to develop new agents with improved anesthetic qualities. Eventually, a nontoxic, rapidly acting agent may become available that could provide profound anesthesia of long duration when applied topically to intact skin
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Current Opinion in Anaesthesiology, 2010
Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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Local anesthetics are not only used as drugs to block the sodium channel to provide analgesia and antiarrhythmic action. The purpose of this review is to highlight the new indications and limitations of this class of drugs.Recent research has focused on the use of intravenous local anesthetics to improve bowel function after surgery or trauma, to ...
Borgeat, A, Aguirre, J
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ABSORPTION OF LOCAL ANESTHETICS
Journal of the American Medical Association, 1958Factors that determine the rate of absorption of a local anesthetic were studied in canine and, when possible, in human subjects. The drugs used were tetracaine, cocaine, procaine, and benzocaine. Objective data was obtained in the form of actual concentrations of each drug in the blood, and the concentrations obtained by intravenous injection were ...
John Adriani, Donovan Campbell
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2006
Local anesthetics are drugs used in many different ways and in various situations requiring local pain relief, beginning with simple procedures, such as removing a small piece of the outer layer of damaged skin, to complicated operations, such as organ transplantations.
V.J. Hruby, R.S. Vardanyan
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Local anesthetics are drugs used in many different ways and in various situations requiring local pain relief, beginning with simple procedures, such as removing a small piece of the outer layer of damaged skin, to complicated operations, such as organ transplantations.
V.J. Hruby, R.S. Vardanyan
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JAMA: The Journal of the American Medical Association, 1969
Patients frequently relate a history suggesting allergy to local anesthetic drugs which have been commonly recognized as causing dermatitis and systemic reactions. 1 However, there appears to be a wide discrepancy between the actual incidence and the emphasis placed on them by textbooks and lectures.
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Patients frequently relate a history suggesting allergy to local anesthetic drugs which have been commonly recognized as causing dermatitis and systemic reactions. 1 However, there appears to be a wide discrepancy between the actual incidence and the emphasis placed on them by textbooks and lectures.
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American Journal of Health-System Pharmacy, 2014
PURPOSE The therapeutic rationale, clinical effectiveness, and potential adverse effects of medications used in combination with local anesthetics for peripheral nerve block therapy are reviewed.
N. Bailard, Jaime Ortiz, R. A. Flores
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PURPOSE The therapeutic rationale, clinical effectiveness, and potential adverse effects of medications used in combination with local anesthetics for peripheral nerve block therapy are reviewed.
N. Bailard, Jaime Ortiz, R. A. Flores
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2014
The Side Effects of Drugs Annuals form a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of relevant publications from January 2012 to June 2013
Sekandarzad, Mir Wais, Schug, Stephan A.
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The Side Effects of Drugs Annuals form a series of volumes in which the adverse effects of drugs and adverse reactions to them are surveyed. The series supplements the contents of Meyler's Side Effects of Drugs: the International Encyclopedia of Adverse Drug Reactions and Interactions. This review of relevant publications from January 2012 to June 2013
Sekandarzad, Mir Wais, Schug, Stephan A.
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Reactions to Local Anesthetics
JAMA: The Journal of the American Medical Association, 1966Local anesthetics are used widely by practically all physicians, most of whom are not fully aware of the lethal potential of local anesthetics and the swiftness with which they may precipitate a catastrophe. The perineural concentration of a local anesthetic necessary to interrupt conduction in a nerve fiber is many times greater than that which a ...
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