Results 101 to 110 of about 33,717 (257)
Investigating the role of the Leishmania (Leishmania) major HASP and SHERP genes during metacyclogenesis in the sand fly vectors, Phlebotomus (Phlebotomus) papatasi and Ph. (Ph.) duboscqi [PDF]
, 2013 Leishmania parasites are the causative agents of a diverse spectrum of infectious diseases termed the leishmaniases. These digenetic parasites exist as intracellular, aflagellate amastigotes in a mammalian host and as extracellular flagellated ...
Doehl, Johannes
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Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Benzimidazole derivatives: search for GI-friendly anti-inflammatory analgesic agents [PDF]
, 2015 Non-steroidal anti-inflammatory drugs (NSAIDs) have been successfully used for the alleviation of pain and inflammation in the past and continue to be used daily by millions of patients worldwide.
Chander Mohan +13 more
core +1 more source
Advanced Materials, EarlyView.Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang +15 more
wiley +1 more source
Antimicrobial Resistance and Stewardship : Local Efforts on a Global Issue [PDF]
Antibiotics revolutionized healthcare worldwide, but their continued application and overuse have resulted in infectious microorganisms becoming resistant to treatment.
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Advanced Materials, EarlyView.A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu +7 more
wiley +1 more source
Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Advanced Materials, EarlyView.Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
Antibody targeted nanoparticles for imaging and therapy of cancer [PDF]
, 2010 The central hypothesis for this thesis is that antibody-targeted superparamagnetic iron oxide nanoparticles (SPIONs) can be used for diagnosis and therapy of cancer.
Vigor, K.L.
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Treatment-Resistant Bacterial Keratitis: Challenges and Solutions
Clinical Ophthalmology, 2020 Sait Egrilmez,1 Şeyda Yildirim-Theveny2 1Private Office, Izmir, Turkey; 2Adiyaman University, Training and Research Hospital, Adiyaman, TurkeyCorrespondence: Sait EgrilmezPrivate Office, 1593/1 Sok.
Egrilmez S, Yildirim-Theveny Ş
doaj
Biointegrated Battery‐Based Electroceuticals
Advanced Materials, EarlyView.Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou +6 more
wiley +1 more source