A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Hospital admissions among adolescents with local authority care experience or special educational needs in England: a population-based cohort study using linked administrative data from health, education and social care services. [PDF]
Blackburn RM +4 more
europepmc +2 more sources
Implementing the English health inequalities agenda: addressing challenges to person-level, cross-sectoral data linkage, access and routine use for local authority public health. [PDF]
George AP, Powell RA, Rao M.
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Assessing the relationship between community resilience and health outcomes: an observational local-authority level study in England. [PDF]
Camacho C, Bower P, Webb RT, Munford L.
europepmc +1 more source
The Distribution of Local Government Finance by Local Authority Level Deprivation [PDF]
Fenton, Alex +2 more
core
Call for action: ten lessons for local authority innovators [PDF]
This publication shares 10 lessons on how to create innovative change in local government from the Creative Councils programme. Key findings New approaches are needed for costly social challenges posed by long–term youth unemployment and ...
core
An Analysis of Local Security Authority Subsystem Services for Windows and Linux
Svetlana A. Golub, Igor Korkin
openalex +2 more sources
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source

