Results 61 to 70 of about 10,561,922 (303)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
General directionality and the local behavior of argumentation semantics [PDF]
In abstract argumentation, the directionality principle conveys the intuition that, for an unattacked set, the choice of arguments that are part of an extension should only depend on the restriction of the framework to that set. Furthermore, having made such a choice, one should be able to select arguments from the rest of the framework so as to get an
Cristian Gratie +2 more
openaire +6 more sources
Compulsory Migration Governance at Local Level: The Case of Istanbul
This article focuses on the increasing role of cities and local governments in migration governance through following the increasing local turn approach in migration studies in recent years.
TOPAL DEMİROĞLU, ELİF
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Altruistic Versus Egoistic Behavior in a Public Good Game [PDF]
This paper analyzes an evolutionary version of the Public Good game in which boundedly rational agents can use imitation and best-reply decision rules. Several possibilities for both decision rules to be present in the population are considered.
Matros, Alexander
core +4 more sources
Local residents’ voices have been regarded as the most important extra-role behavior that determines the growth and survival of tourist destinations. This study examines the antecedents of such crucial extra-role behaviors of local residents. Furthermore,
David Amani
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Local fuse for improving concentric braces behavior
The concentrically braced system is one of the most common lateral load bearing systems among steel structures. These systems have remarkable lateral stiffness and strength, but their compressive buckling prevents them from being ductile and absorbing ...
Ali Kachooee +2 more
doaj +1 more source

