Results 131 to 140 of about 411,823 (288)

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

The Causality and Threshold Levels of Innovative Work and Entrepreneurial Behaviours of Millennial Farmers: Do Family Characteristics Matter?

open access: yesIndonesian Journal of Business and Entrepreneurship
Background: Millennial farmers' innovative and entrepreneurial behaviors have been discussed in the literature. However, the contribution of farmer family characteristics is widely ignored.
Emi Widiyanti, Malik Cahyadin
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Debt and Depression: Evidence on Casual Links and Social Stigma Effects [PDF]

open access: yes
Using individual-level panel data, this paper examines the relationship between problem debt and psychological health. Individuals exhibiting problem debt, by either subjective or objective measures, also exhibit much worse psychological health, by ...
John Gathergood
core  

Invariant Causal Prediction with Local Models

open access: yes
We consider the task of identifying the causal parents of a target variable among a set of candidates from observational data. Our main assumption is that the candidate variables are observed in different environments which may, under certain assumptions, be regarded as interventions on the observed system.
Mey, Alexander, Castro, Rui M.
openaire   +4 more sources

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

Re-testing for financial integration of the Turkish Stock Market and the US Stock Market: An Evidence from co-integration and error correction models [PDF]

open access: yesRevista Română de Statistică, 2017
This paper investigates financial market integration among U.S. stock market and Turkish stock market using monthly data for the period of 1989 to 2015.
Turgut Tursoy, Faisal Faisal
doaj  

Testing for causality in variance using multivariate GARCH models [PDF]

open access: yes
Tests of causality in variance in multiple time serieshave been proposed recently, based on residuals of estimatedunivariate models. Although such tests are applied frequentlylittle is known about their power properties.
Hafner, C.M., Herwartz, H.
core   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

open access: yesAdvanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich   +2 more
wiley   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

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