Results 31 to 40 of about 6,137,682 (288)
Vaccine Research, 2021 Vaccine safety surveillance is important to identify and manage adverse events following immunisation (AEFI) and avoid vaccine hesitancy. Currently, COVID-19 vaccines are administered to large numbers of people to try and curb the pandemic. In this paper,
Shyh Poh Teo
doaj +1 more source
Causality between challenges, availability, and extent of use of local building materials
South African Journal of Science, 2022 The promotion of sustainable practice in construction has resulted in a renewed focus on local building materials (LBMs). However, existing studies have not provided an extensive understanding of the challenges in the use and awareness of the ...
Abimbola Windapo +4 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Global and local aspects of causality in quantum mechanics
EPJ Web of Conferences, 2013 Quantum mechanics forces us to reconsider certain aspects of classical causality. The ‘central mystery’ of quantum mechanics manifests in different ways, depending on the interpretation. This mystery can be formulated as the possibility of selecting part
Stoica Cristinel
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Gravitational causality and the self-stress of photons
Journal of High Energy Physics, 2022 We study causality in gravitational systems beyond the classical limit. Using on-shell methods, we consider the 1-loop corrections from charged particles to the photon energy-momentum tensor — the self-stress — that controls the quantum interaction ...
Brando Bellazzini +3 more
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Reconsidering Relativistic Causality [PDF]
, 2007 I discuss the idea of relativistic causality, i.e. the requirement that causal processes or signals can propagate only within the light-cone. After briefly locating this requirement in the philosophy of causation, my main aim is to draw philosophers ...
Butterfield, Jeremy
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