Results 61 to 70 of about 102,068 (255)

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Testing the relationship between investor risk appetite and country risk: The case of Turkey [PDF]

Panoeconomicus
Country risk is an important factor affecting the risk appetite of investors who want to create an optimal portfolio by minimizing their risks. Investor risk appetite can affect country risk as a factor contributing to the development of financial ...
Kaya Abdulkadir, Gulhan Unal, Gungor Bener   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Local Causal Discovery for Statistically Efficient Causal Inference

CoRR
Causal discovery methods can identify valid adjustment sets for causal effect estimation for a pair of target variables, even when the underlying causal graph is unknown. Global causal discovery methods focus on learning the whole causal graph and therefore enable the recovery of optimal adjustment sets, i.e., sets with the lowest asymptotic variance ...
Mátyás Schubert, Tom Claassen, Sara Magliacane   +2 more
openaire   +2 more sources

Local Characterizations of Causal Bayesian Networks [PDF]

, 2012
The standard definition of causal Bayesian networks (CBNs) invokes a global condition according to which the distribution resulting from any intervention can be decomposed into a truncated product dictated by its respective mutilated subgraph. We analyze alternative formulations which emphasizes local aspects of the causal process and can serve ...
Elias Bareinboim, Carlos Brito 0001, Judea Pearl   +2 more
openaire   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Causal localizations of the massive scalar boson

Letters in Mathematical Physics, 2023
AbstractThe positive operator-valued localizations (POL) of a massive scalar boson are constructed, and a characterization and structural analyses of their kernels are obtained. In the focus of this article are the causal features of the POL. There is the well-known causal time evolution (CT). Recently a POL by Terno and Moretti, which is a kinematical
openaire   +2 more sources

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

A panel data study of causality links between CO2 concentration and temperature

Environmental Research Letters
While the role of rising CO _2 concentration in increasing the temperature is well known, the opposite causality link, from temperature to CO _2 concentration, received far less scrutiny.
Marco Amendola, Umberto Triacca, Marco Valente   +2 more
doaj   +1 more source