Results 31 to 40 of about 283,340 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Infrastructure and automobile shifts: positioning transit to reduce life-cycle environmental impacts for urban sustainability goals

Environmental Research Letters, 2013
Public transportation systems are often part of strategies to reduce urban environmental impacts from passenger transportation, yet comprehensive energy and environmental life-cycle measures, including upfront infrastructure effects and indirect and ...
Mikhail Chester, Stephanie Pincetl, Zoe Elizabeth, William Eisenstein, Juan Matute   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Public Participation in New Local Governance Spaces: The Case for Community Development in Local Strategic Partnerships [PDF]

, 2014
Research into public participation in local decision-making has increased over the past forty years, reflecting increased interest in the subject from academic, policy and practitioner perspectives.
Purcell, Martin, Purcell, Martin E., Martin E. Purcell, Purcell, Martin; id_orcid   +3 more
core   +1 more source

Local Communities Participation in Ecotourism Development

Jurnal Ilmu Kehutanan, 2020
The community forest Mandiri Kalibiru manages of protected forests one of activities is ecotourism management. The involvement of local communities as ecotourism actors is a major feature in the service business.
Kaharuddin Kaharuddin, Satyawan Pudyatmoko, Chafid Fandeli, Wisjnu Martani   +3 more
doaj   +1 more source

Agrarian Archaeology: A Research and Social Transformation Tool

Heritage, 2022
The aim of this paper is to approach the concept of agrarian archaeology, an epistemological framework that allows the investigation of agrarian landscapes favouring new historical narratives far from traditional paradigms and, at the same time, the ...
Margarita Fernández Mier, Jesús Fernández Fernández, Pablo López Gómez   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Local Community

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT
I.     ABSTRACT Local Community is a mobile application created to help in a local area share information and support each other. Sometimes people need quick help, such as blood donation, finding lost items, or getting information about nearby services. In many cases, it is difficult to inform others in the community quickly.
Ms. Bhandare Harshda Sunil, Vardhave Ruchita Prashant, Ms. Rodage Srushti Shrishail, Ms, Dhulam Rekha Pandharinath, Ms. Bhinge Sanjana Mallikarjun, Ms. Kalshetti Priti Dayanand, Ms. Durshetti Rachana Ravindra   +6 more
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Online communities and their contribution to local heritage knowledge [PDF]

, 2020
peer reviewedThe purpose of this study is to explore the potential of social media as a framework for people-centered heritage. With a focus on the interpretation and display of heritage by online communities, this paper aims at providing insights into ...
Teller, Jacques, Ginzarly, Manal
core   +1 more source