Results 161 to 170 of about 1,432,258 (269)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Consumer and Health Care Professional Perspectives on a Digital Platform to Support Preventive Antenatal Care: Qualitative Descriptive Study. [PDF]

JMIR Form Res
Doherty E, Dilworth S, Rice A, Wedesweiler T, Shrestha R, Greenwood S, Foster M, Lewis J, Daly J, Wyse R, Mallise C, Kingsland M.   +11 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

β-carotene enhances drought tolerance in fenugreek by modulating antioxidant defense and redox homeostasis. [PDF]

Plant Signal Behav
Hussain M, Ramzan T, Shahbaz M, Haider A, Ahmad M, Waraich EA, Zulfiqar U, El-Beltagi HS, Alasmari A, Alotaibi MS, Gururani MA.   +10 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Digital Support for Cancer Caregivers in Latin America: Identifying Needs and Co-Designing a Culturally Adapted Resource. [PDF]

Psychooncology
Carreño-Moreno S, Chaparro-Diaz L, Taylor C, Santin O.   +3 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Influence of Piau and commercial genetic groups on the performance, carcass traits, and meat quality of pigs. [PDF]

Trop Anim Health Prod
de Cássia Miranda Dias LC, Lopes PS, da Silva Bernardo RM, Abreu CP, de Freitas GH, Chizzotti ML, da Silva DA, Marques DBD, Veroneze R.   +8 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Performance of Multi-Gradient Biomimetic POSS-Toughened CFRP Laminates with a Pearl-Inspired Hard-Soft Interfacial Architecture. [PDF]

Polymers (Basel)
Xiang G, Sun S, Wang Y, Jia B, Li C, Qin M.   +5 more
europepmc   +1 more source