Results 81 to 90 of about 1,369,246 (269)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Sustainability, Corporate Community Engagement and Enterprise Development – Lessons from a Case Study in Emu-Ebendo Niger-Delta, Nigeria

open access: yesProblemy Ekorozwoju, 2017
Corporate community engagement remains an under researched area in sustainability debates.  Presenting a case study, based on in-depth interviews and site visits, of how one indigenous company Energia Ltd has formed a strong partnership or bond with the
O.E. Ajide   +3 more
doaj  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Local content in Brazil: conceptual framework and methodological implications

open access: yesDigithum, 2009
This article presents work in progress from PhD research investigating the use of the internet in the favelas (shantytowns) of Rio de Janeiro, Brazil, with a particular focus on the internet content produced and shared by those who live there.
Tori Holmes
doaj  

Local Queuing Under Contention.

open access: yes, 2018
We study stability of local packet scheduling policies in a distributed system of n nodes. The local policies at nodes may only access their local queues, and have no other feedback from the underlying distributed system. The packets arrive at queues according to arrival patterns controlled by an adversary restricted only by injection rate rho and ...
Pawel Garncarek   +2 more
openaire   +3 more sources

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Development of Website-Based Digital Teaching Materials for the Jarimatika Qur'an Method: A Local Content Integration Approach

open access: yesTarbawi
This study employs a research and development approach to identify the need, design, validity, practicality, and effectiveness of website-based digital teaching materials for the Jarimatika Qur'an Method as local content.
Rizki Muthmainnah Amir   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Varieties of local content: Comparing ideas and institutions in Brazil and Malaysia’s oil and gas sector

open access: yesBusiness and Politics
Local content policies (LCPs) are key instruments of industrial policy used by middle-income countries (MICs) to capture segments of global value chains (GVCs). While, in principle, LCPs are very similar, in practice, they are highly diverse.
Yuri Kasahara   +2 more
doaj   +1 more source

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