Results 111 to 120 of about 12,880,017 (293)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Penerapan Material Bahan Bangunan dan Konsep Pemaknaan pada Gereja Puh Sarang sebagai Warisan Budaya Indonesia

open access: yesHumaniora, 2011
Puh Sarang Church which located at Kediri, East Java, Indonesia, who’s made by Henri Maclaine Pont, give an illustrated of case study, how the Church developed with a good and great idea from the Architect which his effort to revitalized a local mind (
Grace Hartanti
doaj  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

The baryon content of the local intergalactic medium

open access: yes, 2006
We describe our surveys of low column density Lyman-alpha absorbers [N(HI) = 10^(12.5-16.0) cm^-2], which show that the warm photoionized IGM contains 30% of all baryons at z < 0.1. This fraction is consistent with cosmological simulations, which also predict that an additional 20-40% of the baryons reside in hotter 10^(5-7) K gas, the warm-hot IGM (
Stocke, John T.   +2 more
openaire   +2 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Proximate Analysis¸ Minerals, Tannin and Phytate Content of Some Local and Imported Legume Seeds [PDF]

open access: yes, 2011
The present study was designed to determine the nutrient composition of some Local and Imported Legume seeds. Seeds of ten legume crops, namely local and imported faba bean (Vicia faba), field pea (Pisum sativum), chickpea (Cicer arietnum),lupin ...
Elgaili Ali Ebrahim, Nahla
core  

Indigenous knowledge dataset of Dayak, Malay and Chinese communities in Sintang Regency, West Kalimantan, Indonesia

open access: yesData in Brief
The dataset in this article presents indigenous knowledge of Dayak, Malay, and Chinese ethnic communities in Sintang Regency, West Kalimantan, Indonesia.
Adriana Gandasari   +8 more
doaj   +1 more source

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