Results 91 to 100 of about 1,369,246 (269)

INTERNALISASI NILAI-NILAI KEARIFAN LOKAL PADA PELAJARAN BAHASA JAWA DI SEKOLAH DASAR

Profesi Pendidikan Dasar, 2019
Local wisdom is supposed to be a basic guideline for people to live their life in the surround society. Recently, media emerges and discusses on the survival of the local wisdom throughout the Indonesian society. This research is trying to review how the
Yanti Haryanti, Honest Ummi Kaltsum
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Utilization of Interactive Schistosomiasis Educational Media in Changing Clean and Healthy Living Behaviors to Prevent Stunting

Journal of Public Health and Pharmacy
Introduction: Schistosomiasis disease infecting humans in Indonesia is caused by the trematode worm Schistosoma japonicum type with the intermediate host being the snail Oncomelania hupensis lindoensis.
Ahmad Erlan, Paisal Paisal, Yona Patanduk, Muhammad Firdaus, Anggri Alfira Yunita Assa, I Kadek Wartana, Veni Mornalita Kolupe, Sitti Fajrah, Niluh Desy Purnamasari, Desak Eka Susianawati, Fitri Arni   +10 more
doaj   +1 more source

The Implementation of Islamic Local Content in Building Character Education at Junior High Shcool Al Amanah Bandung

Jurnal Pendidikan Islam, 2019
Education system constitutes an important stage in growing, developing, and strengthening the character of younger generation. This means that the objectives of education at the institutional level (school) can be a representation of the goals of ...
Mohamad Erihadiana
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Penerapan Material Bahan Bangunan dan Konsep Pemaknaan pada Gereja Puh Sarang sebagai Warisan Budaya Indonesia

Humaniora, 2011
Puh Sarang Church which located at Kediri, East Java, Indonesia, who’s made by Henri Maclaine Pont, give an illustrated of case study, how the Church developed with a good and great idea from the Architect which his effort to revitalized a local mind (
Grace Hartanti
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source