Results 101 to 110 of about 1,432,258 (269)

ANALISIS EFEKTIVITAS IKLAN-IKLAN TV BERTEMA LOCAL CONTENT DI INDONESIA TAHUN 2004

Nirmana, 2007
In the globalization era, local content TV commercials are considered to be more and more important. This thesis aims to analyze how far the local content TV commercials can be accepted by the Indonesian audience, who are culturally diverse; moreover ...
Bernadette Dian Arini Maer, Bing Bedjo Tanudjaja, Baskoro Suryo Banindro   +2 more
doaj  

Transformational Leadership and the Strengthening of Positive School Culture Based on Minangkabau Local Values

Jurnal Socius: Journal of Sociology Research and Education
This study examines how the integration of principals’ transformational leadership with Minangkabau cultural values serves as a constructive strategy for strengthening a positive school culture. The study addresses a gap in the literature, as research on
Defril Syafrin, Nurhizrah Gistituati, Rusdinal Rusdinal, Nellitawati Nellitawati   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Kurikulum Muatan Lokal Aksara Arab Melayu dalam Meningkatkan Literasi Melalui Kearifan Lokal di Kota Jambi

Arabi: Journal of Arabic Studies
This study aims to explain the Local Content Curriculum of Arabic-Malay Script in Improving Literacy Through Local Wisdom at the Nurul Iman Seberang Islamic School in Jambi City.
Eva Iryani, Agung Yusup, Salman Jufri, Tuti Hardianti Hasibuan, Nurazzelena Nurazzelena   +4 more
doaj   +1 more source

Conscious Vision Proceeds from Global to Local Content in Goal-Directed Tasks and Spontaneous Vision. [PDF]

J Neurosci, 2016
Campana F, Rebollo I, Urai A, Wyart V, Tallon-Baudry C.   +4 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Managing Local Wisdom-Based Curriculum: An Integrative Framework for Madrasah Education

Al-Tanzim: Jurnal Manajemen Pendidikan Islam
This study aims to analyze and develop a curriculum model grounded in local wisdom for madrasas. The study focuses on curriculum planning, implementation, and evaluation, as well as a comparison of implementation across two madrasas.
Cut Irhamna Heriyanti, Amiruddin Siahaan, Siti Halimah   +2 more
doaj   +1 more source