Results 81 to 90 of about 5,430,702 (304)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Education system constitutes an important stage in growing, developing, and strengthening the character of younger generation. This means that the objectives of education at the institutional level (school) can be a representation of the goals of ...
Mohamad Erihadiana
doaj +1 more source
Measuring Digital Local Content [PDF]
This paper discusses the ways to quantify the local content that can be delivered through the internet. Several indicators are proposed; for each indicator the paper discusses available data, presents strengths of a given measure and outlines its potential drawbacks.
openaire +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Strenthening local food systems: tracing learning of knowledge and skills by content and discourse analysis [PDF]
The local food systems meet the food systems of scale on the local market, where the local and regional chains are looking for ways to survive and even to strengthen.
Mikkola, Minna
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
American Studies in Indonesia: Global or Local Content?
The curriculum of the American Studies Program at The School of Strategic and Global Studies of the University of Indonesia comprises among others conversations on American Philosophy, American Democracy, American Culture, American Politics, American ...
Inkiriwang, Riani E. +1 more
doaj +1 more source
Local content of bipartite qubit correlations
One of the last open problems concerning two qubits in a pure state is to find the exact local content of their correlation, in the sense of Elitzur, Popescu and Rohrlich (EPR2) [Phys. Lett. A 162, 25 (1992)]. We propose a new EPR2 decomposition that allows us to prove, for a wide range of states psi(theta)=cos(theta)|00>+sin(theta)|11>, that ...
Branciard, Cyril +2 more
openaire +6 more sources

