Results 41 to 50 of about 1,311,159 (211)
Sickness Absence and Local Cultures [PDF]
Sickness absence has been found to vary substantially across geographical areas. There are large differences between different countries but also between different regions within a particular country.
Bokenblom, Mattias, Ekblad, Kristin
core
INCORPORATING LOCAL WISDOM INTO ENGLISH LANGUAGE TEACHING (ELT) [PDF]
, 2013 Since language (e.g.local languages)is an important part of a culture, it should be maintained and revitalized. When the language undergoes attrition because of global culture, many aspects in culture will also be extinct.
Suharno, Suharno
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Rethinking International Compensation: From Expatriate and National Cultures to Strategic Flexibility [PDF]
, 1997 [Excerpt] We are on the verge of a worldwide restructuring of compensation and reward systems. Even long established, seemingly carved-in-granite cultural norms, such as lifetime employment in Japan and industry-wide bargaining in Germany, are weakening ...
Bloom, Matthew C. +1 more
core +1 more source
The Mobility and/or Fixity of Urban and Planning Policies – The Role of Divergent Urban Planning Cultures [PDF]
, 2014 Cities and regions are increasingly interconnected on a global scale. In the process of the making of cities and regions policy actors increasingly rely on globally flowing and very mobile urban policy models, which have been originally developed in ...
Hamedinger, Alexander
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
When does defection pay?: The stability of institutional arrangements in clusters [PDF]
, 2018 The present paper investigates cluster adjustment to changing economic environments by focussing on the role and stability of institutional arrangements in their local culture.
Press, Kerstin
core
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source