Results 21 to 30 of about 2,387,934 (264)

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression

Cell Death and Disease, 2023
Programmed death-ligand 1 (PD-L1) ensures that tumor cells escape T-cell-mediated tumor immune surveillance. However, gliomas are characteristic of the low immune response and high-resistance therapy, it is necessary to understand molecular regulatory ...
Shengwen Long, Guixiang Huang, Mi Ouyang, Kai Xiao, Hao Zhou, Anyi Hou, Zhiwei Li, Zhe Zhong, Dongmei Zhong, Qinghao Wang, Shuanglin Xiang, Xiaofeng Ding   +11 more
doaj   +1 more source

CLLD in the 2014–2020 EU Programming Period: An Innovative Framework for Local Development

World, 2023
This paper presents an overview of how the Community-led Local Development (CLLD) instrument has been used in the EU in the 2014–2020 programming period. It provides a typology of countries applying the options offered by CLLD and illustrates the various
Stefan Kah, Haris Martinos, Urszula Budzich-Tabor   +2 more
doaj   +1 more source

The development of synaptic transmission is time-locked to early social behaviors in rats

Nature Communications, 2019
The development of functional synapses is a key milestone in neurodevelopment. Here, the authors show how serotonin signalling coordinates development of glutamatergic and GABAergic currents and triggers the emergence of integrative behavior (huddling ...
Shovan Naskar, Roberto Narducci, Edoardo Balzani, Andrzej W. Cwetsch, Valter Tucci, Laura Cancedda   +5 more
doaj   +1 more source

Financial inclusion and stability in Ethiopia using bank-level data: A two-step system GMM estimation [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research
Background This paper examines the impact of FI on bank stability within Ethiopian context, using panel data from 17 commercial banks over the period 2015-2023.
Andualem Mekonnen, Filmon Hando, Mohammed Arebo   +2 more
doaj   +1 more source

Correction: Serrano, J.J.; Esparcia, J. Diagnosis of Rural Development Processes Based on the Stock of Social Capital and Social Networks: Approach from E-I Index. Land 2023, 12, 850

Land, 2023
In the original publication [...]
J. Javier Serrano, Javier Esparcia
doaj   +1 more source

Family Storytelling and Local Development

Fuori Luogo, 2022
As is known, for many years now, the economic and social development of urban areas, whether large or small, has been increasingly linked to the presence and level of diffusion of the tourist phenomenon. In such contexts, it is therefore extremely important for public governance to spend as fully as possible in creating situations that make one’s urban
Perri A., Romita T.
openaire   +3 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Recent Developments in Local Helioseismology [PDF]

Solar Physics, 2008
Local helioseismology is providing new views of subphotospheric flows from supergranulation to global-scale meridional circulation and for studying structures and dynamics in the quiet Sun and active regions. In this short review we focus on recent developments, and in particular on a number of current issues, including the sensitivity of different ...
Thompson, M.J., Zharkov, S.
openaire   +2 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source