Results 61 to 70 of about 6,762,995 (257)

Regulatory role of non-coding RNA in ginseng rusty root symptom tissue

open access: yesScientific Reports, 2021
Ginseng rusty root symptom (GRS) is one of the primary diseases of ginseng. It leads to a severe decline in the quality of ginseng and significantly affects the ginseng industry.
Xingbo Bian   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Inherent fast inactivation particle of Nav channels as a new binding site for a neurotoxin

open access: yesThe EMBO Journal
Neurotoxins derived from animal venoms are indispensable tools for probing the structure and function of voltage-gated sodium (Nav) channels. Utilizing a novel centipede peptide toxin called rpTx1, we show that the “inherent inactivation particle” of Nav
Xi Zhou   +23 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

National Innovation System (NIS) as a Means for Development: Policies, Opportunities, and Challenges in Ethiopia. [version 2; peer review: 2 approved, 1 approved with reservations]

open access: yesF1000Research
Introduction A robust National Innovation System (NIS) has become crucial for fostering socioeconomic progress and competitiveness in emerging economies like Ethiopia, and its success relies significantly on successful implementation of science ...
Ashenafi Bayinesagn   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Malaysian local governments’ role towards sustainable development focusing on knowledge transfer practices framework [PDF]

open access: yes, 2014
Local Governments are facing very demanding and dynamic situation in development agenda when dealing with sustainable development. When the development’s activities do not start with the sustainability elements at Local Governments, the negative ...
Mohamed, Sulzakimin
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Temporal transcriptomic and proteomic characterization of adipose tissue from cold-exposed mice

open access: yesScientific Data
Cold stimulation has emerged as a promising therapeutic strategy against obesity by activating thermogenesis. Although the metabolic responses of adipose tissue to cold are well documented, the dynamic transcriptional and proteomic changes that occur in ...
Qiuyan Zhu   +8 more
doaj   +1 more source

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