Results 71 to 80 of about 9,120,391 (361)

A Scorpion Peptide Exerts Selective Anti-Leukemia Effects Through Disrupting Cell Membranes and Triggering Bax/Bcl-2-Related Apoptosis Pathway

Biomolecules
Numerous modern scientific studies have demonstrated that animal venoms harbor a wealth of diverse anticancer active components, serving as a valuable resource for the development of natural antitumor drugs.
Xiaoping Dong, Siwei Yi, Yaqin Yang, Yushuo Wang, Lingxiang Wang, Jingjing Huang, Yong Zeng, Zhonghua Liu   +7 more
doaj   +1 more source

Challenges in local governance: Public-private partnerships as an instrument for local transport policies

Studia z Polityki Publicznej, 2020
Public-private partnerships (PPP) as suppliers for public services have been increasingly used as an instrument for improving public policy, mostly when it comes to reducing costs and improving public transport.
Everardo Chiapa Aguillón
doaj   +1 more source

Local financial development and growth [PDF]

Using a unique sample of net domestic product data for districts in India, I investigate the connection between banking sector development, human capital, and economic growth at the sub-national level.
Kendall, Jake
core  

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Temporal transcriptomic and proteomic characterization of adipose tissue from cold-exposed mice

Scientific Data
Cold stimulation has emerged as a promising therapeutic strategy against obesity by activating thermogenesis. Although the metabolic responses of adipose tissue to cold are well documented, the dynamic transcriptional and proteomic changes that occur in ...
Qiuyan Zhu, Shuo Wang, Hao Zhou, Jianbo Yang, Yangya Liang, Xi Chen, Jianlin Zhou, Dandan Wu, Xing Zhang   +8 more
doaj   +1 more source

FINANCING LOCAL DEVELOPMENT [PDF]

Community/Rural/Urban Development,
Coetzee, Gerhard K., Fournier, Y., Gentil, D., Perret, Sylvain R.   +3 more
core   +1 more source

Supporting Survivor‐Centered Care Through Digital Health Integration

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak, Rebecca Williamson‐Lewis, Michael O'Connor, Michael Palgon, Yu‐Ra Kim, Michael Schuckenbrock, Paula Edwards, Abraham Mendoza, Anthony Adams, Brian Arriaga‐Solis, Justin Parker, Harry Tinoco‐Giraldo, Jason King, C. Michael Fordis, Karen E. Effinger, Maria Monica Gramatges   +15 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Morphometric Indicators for the Definition of New Territorial Units in the Periurban Space: Application to the Metropolitan Area of Valencia (Spain)

Land
New territorial units resulting from urban sprawl processes constitute a major challenge for territorial planning. The aim of this paper is to analyze periurban spaces, focusing on the delimitation and characterization of the urban units arising from ...
Julia Salom-Carrasco, Carmen Zornoza-Gallego   +1 more
doaj   +1 more source

Local Economic Development Policies [PDF]

This chapter seeks to provide useful advice for local government policy towards economic development programs. The chapter: reviews the size and scope of local economic development programs in the United States; critically analyzes the various rationales
Timothy J. Bartik
core   +1 more source