Results 91 to 100 of about 2,387,934 (264)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Beyond the Economy: Metropolitan Mobility and the Relevance of the Peak-Car Concept
European Journal of GeographyDaily mobility in urban areas is crucial for the successful implementation of an energy transition aligned with decarbonisation and sustainability objectives.
Juan M. Albertos, Carmen Zornoza
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Are local development plans mainstreaming climate-smart agriculture? A mixed-content analysis of medium-term development plans in semi-arid Ghana. [PDF]
Socioecol Pract Res, 2021 Diko SK +5 more
europepmc +1 more source
The role of universities in local development
Corvinus Journal of Sociology and Social Policy, 2014 The paper deals with the role that universities can have in promoting innovation in general and at local and regional level in particular. In doing this, the nature of universities and the quality of their relations to industry and governments is of paramount importance. During the last three decades university-industry relationships and the supportive
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjective Limited land use resource and arrangement adjacent to operational high-speed railway lines pose significant challenges to some city foundation pit constructions and the railway operational safety.
LI Xiaolong +5 more
doaj +1 more source
BJS Open, 2019 Background End colostomy rates following colorectal resection vary across institutions in high‐income settings, being influenced by patient, disease, surgeon and system factors.
GlobalSurg Collaborative +10 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Genomic evolution of enteric pathogens: mechanisms of pathogenicity and diagnostic innovations
Frontiers in MicrobiologyGenomic evolution serves as a pivotal driver of pathogenicity and host adaptation in intestinal pathogens. This review systematically dissects, from a phylogenetic perspective, the key genomic evolutionary mechanisms underpinning pathogenesis across five
Tao Li +10 more
doaj +1 more source