Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
PATRIOTIC STRATEGY OF LOCAL POLITICAL DEVELOPMENT: INSTITUTIONAL AND MOTIVATIVE FUNDAMENTALS
B.A. Filatov
openalex +1 more source
How do local-level legal institutions promote development ? [PDF]
This paper develops a framework and some hypotheses regarding the impact of local-level, informal legal institutions on three economic outcomes: aggregate growth, inequality, and human capabilities.
Gauri, Varun
core
Local Economic Development Incentives in New York City [PDF]
This report provides the first systematic and comprehensive analysis of datasets on economic development incentives in New York City over the last fifteen ...
Franz Fuerst
core
Sustainable local development and agri-food system in the post Covid crisis: The case of Rome. [PDF]
Cavallo A, Olivieri FM.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Contribution of Local Tribun Newspaper to Development Progress In Bone District
Hasrullah Andi Asdar
openalex +2 more sources
Sea level rise adaptation: emerging lessons for local policy development [PDF]
Many coastal communities across the United States are beginning to plan for climate-related sea level rise. While impacts and solutions will vary with local conditions, jurisdictions which have begun this process seem to pass through three common stages ...
Lausche, Barbara J., Maier, Luke
core
Prevalence of Congenital Anomaly and Its Relationship with Maternal Education and Age According to Local Development in the Extreme South of Brazil. [PDF]
Anele CR +3 more
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

