Results 111 to 120 of about 3,027,964 (314)

Local innovation systems in Poland - the beginning of the road

Miscellanea Geographica: Regional Studies on Development, 2017
Local innovation systems (LIS) constitute a relatively new term as usually the discussion about the systemic approach to innovation has focused on the level of countries, and most of all - regions.
Dziemianowicz Wojciech, Laskowska Agnieszka, Peszat Klaudia   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

IDB-DC Community Link: No. 16 : August 1, 2008

, 2008
This e-bulletin IDB-DC Solidarity Program is an initiative of the Inter-American Development Bank (IDB). It builds strategic partnerships with local community-based organizations to promote community development initiatives aimed at the Hispanic and ...
Inter-American Development Bank
core   +1 more source

Deletion of Tfap2a in hepatocytes and macrophages promotes the progression of hepatocellular carcinoma by regulating SREBP1/FASN/ACC pathway and anti-inflammatory effect of IL10

Cell Death and Disease
The transcription factor AP-2α plays a crucial role in the control of tumor development and progression, and suppresses the proliferation and migration of hepatocellular carcinoma (HCC).
Zhiwei Li, Chun Zhang, Guixiang Huang, Zixin Zhang, Qinghao Wang, Xiran Liu, Yanling Qin, Hao Zhou, Anyi Hou, Jun He, Limin Li, Xiang Hu, Xiaofeng Ding   +12 more
doaj   +1 more source

Exploring the impacts of local development initiatives on tourism: A case study analysis. [PDF]

Heliyon, 2023
Gemar G, Soler IP, Moniche L.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluating the Effectiveness of Rhizobium Inoculants and Micronutrients as Technologies for Nepalese Common Bean Smallholder Farmers in the Real-World Context of Highly Variable Hillside Environments and Indigenous Farming Practices

Agriculture, 2019
Studies have shown the potential of rhizobia and associated micronutrients to enhance symbiotic nitrogen fixation in legumes. Tens of millions of smallholder farmers, however, farm on mountain hillsides in highly variable soil and microenvironments, with
Malinda S. Thilakarathna, Tejendra Chapagain, Bhawana Ghimire, Roshan Pudasaini, Bir Bhahadur Tamang, Khem Gurung, Khem Choi, Laxmi Rai, Samjhana Magar, Bishnu BK, Shankar Gaire, Manish N. Raizada   +11 more
doaj   +1 more source

Crafts as a key factor in local development: Bibliometric analysis. [PDF]

Heliyon, 2023
Fernández Bellver D, Prados-Peña MB, García-López AM, Molina-Moreno V.   +3 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Consultation on ‘Local Strategic Partnerships : shaping their future’ : response from the Sustainable Development Commission

, 2012
Sustainable Development Commission Response to the Office of the Deputy Prime Minister’s consultation paper on the future of Local Strategic Partnerships entitled ‘Local Strategic Partnerships : shaping their future’.Publisher ...
Sustainable Development Commission
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