Results 131 to 140 of about 9,120,391 (361)

Genomic evolution of enteric pathogens: mechanisms of pathogenicity and diagnostic innovations

Frontiers in Microbiology
Genomic evolution serves as a pivotal driver of pathogenicity and host adaptation in intestinal pathogens. This review systematically dissects, from a phylogenetic perspective, the key genomic evolutionary mechanisms underpinning pathogenesis across five
Tao Li, Jin Li, Zhiping Tang, Xing Liu, Shiwen Yao, Jiabao Zhu, Wei Wang, Linju Huo, Song Chen, Gaihua Zhang, Zhonghua Liu   +10 more
doaj   +1 more source

Neoliberal governance, sustainable development and local communities in the Barents Region [PDF]

, 2014
There are currently high hopes in the Barents Region for economic growth, higher employment and improved well-being, encouraged by developments in the energy industry, tourism and mining.
Ejdemo, Thomas, Espiritu, Aileen A., Fors, Bjarge Schwenke, Korchak, Elena, Nosova, Tatiana, Riabova, Larissa, Tennberg, Monica, Tonkova, Elena, Vola, Joonas   +8 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Knowledge Management As an Economic Development Strategy [PDF]

, 2001
The United States is shifting to an information economy. Productive capability is no longer completely dependent on capital and equipment; information and knowledge assets are increasingly important. The result is a new challenge to the practice of local
Kenan Patrick Jarboe
core  

DETERMINANTS OF LOCAL DEVELOPMENT STRATEGIES

Acta Scientiarum Polonorum. Oeconomia, 2018
The article seeks to specify the extent to which municipal development strategies form the basis for municipality development and what determines these strategies and development processes at the local level. It discusses the following issues: the nature and objectives of local development strategies, characteristics of the development strategy in the
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Does Local Financial Development Matter? [PDF]

We study the effects of differences in local financial development within an integrated financial market. To do so, we construct a new indicator of financial development by estimating a regional effect on the probability that, ceteris paribus, a ...
Luigi Guiso, Luigi Zingales, Paola Sapienza   +2 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Classification of Coastal Benthic Substrates Using Supervised and Unsupervised Machine Learning Models on North Shore of the St. Lawrence Maritime Estuary (Canada)

Geomatics
Classification of benthic substrates is a core necessity in many scientific fields like biology, ecology, or geology, with applications branching out to a variety of industries, from fisheries to oil and gas.
Guillaume Labbé-Morissette, Théau Leclercq, Patrick Charron-Morneau, Dominic Gonthier, Dany Doiron, Mohamed-Ali Chouaer, Dominic Ndeh Munang   +6 more
doaj   +1 more source

Differences between supplier development programme of foreign and local Malaysian automotive suppliers [PDF]

, 2011
Research into supplier development has raised issues on the buyer’s relationship with the supplier.A buyer with collaborative relationship would have more interest in supplier development.From the viewpoint of the suppliers, buyers who provided ...
Abdul Kadir, Kadzrina, Ali, Hassan
core