Results 141 to 150 of about 3,027,964 (314)

Prevention, Retention & Contingency Development Reserve (PRCDR) summary of projects

open access: yes, 2000
Title from covers of PDF documents (viewed June 21, 2006).; "The Institute for Local Government Administration and Rural Development (ILGARD) at Ohio University prepared this report for the Ohio Department of Job and Family Services in cooperation with ...
Ohio University. Institute for Local Government Administration and Rural Development.
core  

Beyond the Economy: Metropolitan Mobility and the Relevance of the Peak-Car Concept

open access: yesEuropean Journal of Geography
Daily mobility in urban areas is crucial for the successful implementation of an energy transition aligned with decarbonisation and sustainability objectives.
Juan M. Albertos, Carmen Zornoza
doaj   +1 more source

The role of universities in local development

open access: yesCorvinus Journal of Sociology and Social Policy, 2014
The paper deals with the role that universities can have in promoting innovation in general and at local and regional level in particular. In doing this, the nature of universities and the quality of their relations to industry and governments is of paramount importance. During the last three decades university-industry relationships and the supportive
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Local Development Benefits from Staging Global Events: Achieving the Local Development Legacy from 2012

open access: yes, 2010
A peer review of the Olympic and Paralympic legacy for East London proposed by the Department of Communities and Local Government, United ...
MacRury, Iain, Poynter, Gavin
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Preferential allosteric modulation of Otop1 channels by small molecule compounds

open access: yesCommunications Biology
The Otopetrin (Otop) proteins, comprising Otop1-3, are proton-gated proton channels with key biological functions. Otop1 acts as a receptor for sour and ammonium salt tastes in mammals, but its gating mechanisms and pharmacology remain poorly understood.
Xiangjin Kong   +10 more
doaj   +1 more source

Deformation Control for Foundation Pit Segmented Construction Adjacent to Operational High-speed Railway Lines

open access: yesChengshi guidao jiaotong yanjiu
Objective Limited land use resource and arrangement adjacent to operational high-speed railway lines pose significant challenges to some city foundation pit constructions and the railway operational safety.
LI Xiaolong   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy