Results 161 to 170 of about 9,120,391 (361)

Governance Structures for Local Economic Development in Croatia [PDF]

open access: yes
Who should take care of local economic development in Croatia? This question seems trivial, however, there are still some open questions. According to current legislation, local economic development is an administrative task of the 21 counties, the ...
Ivana Rasic-Bakaric   +2 more
core  

The Development of Historical Instruction/Teaching Material in Senior High Schools Based on Local History with SOI Approach [PDF]

open access: yes, 2013
Purpose: The purpose of this research is to develop more comprehensive model of historical instructional materials that is a model of local history-based teaching materials and oriented to local historical events. The method used in the development
Djono,
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Gender and Remittances: Creating Gender-Responsive Local Development: The Case of Lesotho [PDF]

open access: yes, 2007
The number of international migrants passed 200 million in 2008, more than double the figure in 1965. As the number of migrants continues to grow, the character of international migration has been transformed. South-South migration, as it is now commonly
Crush, Jonathan   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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