Results 31 to 40 of about 950,808 (264)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

A constituição do Pólo Moveleiro de Lucas do Rio Verde (MT): uma retrospectiva histórica de uma iniciativa coletiva de desenvolvimento local e regional

open access: yesCadernos EBAPE.BR
Este artigo descreve e analisa o processo de formação e desenvolvimento do Pólo Moveleiro de Lucas do Rio Verde (MT), a partir de um estudo histórico-biográfico de um conjunto de pequenas e médias empresas que buscaram na parceria e na ação associativa a
Jorge Oneide Sausen   +1 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

El turismo orientado a los pobres: una alternativa estratégica para los países en desarrollo [PDF]

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2012
Initiatives related to Pro Poor Tourism movement have been developed during more than a decade in different regions of the world. Millions of poor people live in places which are potentially destinations and tourism is considered a relevant factor to ...
Olimpia Jiménez López   +1 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tourism development, touristic local taxes and local human resources: A stable way to improve efficiency and effectiveness of local strategies of development

open access: yesAcademicus International Scientific Journal, 2012
The desire to belong in a individual culture means to possess a clear vision for the world, a road map that guides its followers towards the proper understanding of the planet’s past present and future.
Arta Musaraj
doaj   +1 more source

Including Citizen Participation Formats for Drafting and Implementing Local Sustainable Development Strategies

open access: yesUrban Science, 2020
Since the publication of the United Nations’ Sustainable Development Goals, governance for sustainable development has grown and several national, regional and local sustainable development strategies have been adopted.
Christine Meschede, Agnes Mainka
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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