Results 171 to 180 of about 1,348,351 (267)

FeatureDock for protein-ligand docking guided by physicochemical feature-based local environment learning using transformer. [PDF]

NPJ Drug Discov
Xue M, Liu B, Cao S, Huang X.
europepmc   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Enhanced O-glycosylation site prediction using explainable machine learning technique with spatial local environment. [PDF]

Bioinformatics
Hong S, Chattaraj KG, Guo J, Trout BL, Braatz RD.   +4 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Atomistic Electrocatalysts for Modulating the Oxygen Reduction Reaction Selectivity in Carbon-Based Materials: Active-Site Engineering, Local Environment, and Magnetism. [PDF]

ACS Mater Au
Romo-Herrera JM, Guerrero-Sanchez J.
europepmc   +1 more source

Archaeobotanical and isotopic analyses of waterlogged remains from the Neolithic pile-dwelling site of Zug-Riedmatt (Switzerland): Resilience strategies of a plant economy in a changing local environment. [PDF]

PLoS One, 2022
Steiner BL, Martínez-Grau H, Bernasconi SM, Gross E, Hajdas I, Jacomet S, Jaggi M, Schaeren GF, Antolín F.   +8 more
europepmc   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Local environment in biomolecular condensates modulates enzymatic activity across length scales. [PDF]

Nat Commun
Gil-Garcia M, Benítez-Mateos AI, Papp M, Stoffel F, Morelli C, Normak K, Makasewicz K, Faltova L, Paradisi F, Arosio P.   +9 more
europepmc   +1 more source

Exploring Associations Between Children's Obesogenic Behaviors and the Local Environment Using Big Data: Development and Evaluation of the Obesity Prevention Dashboard. [PDF]

JMIR Mhealth Uhealth, 2021
Filos D, Lekka I, Kilintzis V, Stefanopoulos L, Karavidopoulou Y, Maramis C, Diou C, Sarafis I, Papapanagiotou V, Alagialoglou L, Ioakeimidis I, Hassapidou M, Charmandari E, Heimeier R, O'Malley G, O'Donnell S, Doyle G, Delopoulos A, Maglaveras N.   +18 more
europepmc   +1 more source