Results 41 to 50 of about 1,348,351 (267)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
In order to explore the variation law and causes of the humidity effect of local water bodies, this paper selects the data of encrypted automatic weather stations (encrypted stations) and national conventional meteorological stations (conventional ...
Kai Liu +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Chlorodifluoromethane (HCFC-22) is one of the air pollutants that destroy the ozone layer and warm the earth. In order to degrade HCFC-22, the catalytic hydrolysis method is currently the most effective environmental technology.
Xiaofang Tan +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The fundamental principle for protein structuring is that the 3D structure is determined by the amino acid sequence. An important phenomenon in this regard is the presence of a differentiated secondary structure for chain fragments of identical sequence ...
Irena Roterman +4 more
doaj +1 more source
This case study sketches leadership negotiation in Solomon Islands, an archipelago in Melanesia. In Melanesia, kastom, church, and institutional domains compete for influence. School leaders work in the institutional domain but must negotiate with kastom
Kabini Sanga, Martyn Reynolds
doaj +1 more source
Partitioned environments for visual localization
In this paper, we present a novel sequential visual localization algorithm in partitioned route. The algorithm utilizes Monte-Carlo for accurate visual localization. Partitioning the route into several regions produces higher accuracy along with lower computational cost. Each of the regions is represented using independent maps. We use bag-of-words for
openaire +1 more source

