Results 51 to 60 of about 1,348,351 (267)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Security as a foundation for developing the process of resocialization, readaptation and reintegration in the local environment.

open access: yesPolish Journal of Social Rehabilitation, 2018
The text deals with the role of broadly understood security as a necessary foundation for the implementation of the process of resocialization, reintegration and readaptation in the local environment.
Iwona Klonowska
doaj   +1 more source

Närmiljöns betydelse och hur den kan påverkas

open access: yesEducare, 2009
The aim of the present article is to describe how the local environment affects people and how people can have an impact on their local environment. Using the sports movement as an example, the article discusses the importance of getting citizens to ...
Ingegerd Ericsson   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Deciphering the Local Environment of Electrocatalytic Metal Sites with X‐ray Absorption Fine Structure

open access: yesSmall Structures
Electrocatalysis plays a pivotal role in energy conversion and holds significant promise for the development of new energy sources. Understanding the intricate atomic‐level interplay between active sites and electrocatalytic activity is essential for ...
Nan Zhang, Jianqiang Wang
doaj   +1 more source

Image Based Localization in Indoor Environments [PDF]

open access: yes2013 Fourth International Conference on Computing for Geospatial Research and Application, 2013
Image based localization is an important problem with many applications. In our previous work, we presented a two step pipeline for performing image based localization of mobile devices in outdoor environments. In the first step, a query image is matched against a georeferenced 3D image database to retrieve the "closest" image.
Jason Zhi Liang   +3 more
openaire   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Development of a Unique Product

open access: yesIzzivi Prihodnosti, 2021
Purpose and Originality: Tourism in vineyard cottages is new, authentic, unique tourism product, which involves the area of  wine-growing land Posavje, with districts of Dolenjska (Lower Carniola Region), Bela Krajina and Obsotelje-Kozjansko, where are ...
Lea-Marija Colarič-Jakše   +1 more
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The development of synaptic transmission is time-locked to early social behaviors in rats

open access: yesNature Communications, 2019
The development of functional synapses is a key milestone in neurodevelopment. Here, the authors show how serotonin signalling coordinates development of glutamatergic and GABAergic currents and triggers the emergence of integrative behavior (huddling ...
Shovan Naskar   +5 more
doaj   +1 more source

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