Results 71 to 80 of about 1,348,351 (267)

Nouveaux habitants et nouvelles écoles dans les campagnes grecques

open access: yesRevue Internationale d’Éducation de Sèvres
Greek rural communities’ efforts to attract new inhabitants provides an example of an approach that is developing between the social economy and bottom-up informal initiatives, outside or on the fringe of public policies.
Dimitris Goussios
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Local Vulnerability Factors Can Be Used as an Innovative Approach for Developing Inclusive Urban Community Flood Resilience Policies

open access: yesJournal of Flood Risk Management
Rapid urbanisation has resulted in the sealing of pervious surfaces and the construction of houses in flood‐vulnerable areas, aggravating urban flooding.
Connie Susilawati   +6 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Localization in multipath environments [PDF]

open access: yes, 2019
This thesis focuses on the design of localization schemes and algorithms which work in multipath environments. Traditionally, conventional localization schemes work based on the assumption that the reference devices (RDs) are always in Line-of-Sight (LOS) with the mobile device (MD) to locate the MD.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Asthmatic symptoms and air pollution: a panel study on children living in the Italian Po Valley

open access: yesGeospatial Health, 2015
The Po Valley (Northern Italy) has elevated levels of air-pollution due to various sources of pollution and adverse weather conditions. This study evaluates the short-term effects of exposure to particulate matter with a diameter of 10 microns or less ...
Andrea Ranzi   +8 more
doaj   +1 more source

Season naming and the local environment.

open access: yes, 2019
Seasonal patterns vary dramatically around the world, andwe explore the extent to which systems of season categoriessupport efficient communication about the local environment.Our analyses build on a domain-general information-theoreticmodel of categorization across languages, and we identify sev-eral qualitative predictions that emerge when this model
Kemp, Charles   +2 more
openaire   +1 more source

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