Results 81 to 90 of about 1,563,028 (315)
The development of synaptic transmission is time-locked to early social behaviors in rats
Nature Communications, 2019 The development of functional synapses is a key milestone in neurodevelopment. Here, the authors show how serotonin signalling coordinates development of glutamatergic and GABAergic currents and triggers the emergence of integrative behavior (huddling ...
Shovan Naskar +5 more
doaj +1 more source
Progress in Earth and Planetary Science, 2023 Polymodal particle size distributions are generally analyzed by separating them into lognormal distributions, but estimating the precise number of lognormal components required remains a considerable problem.
Naofumi Yamaguchi
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Spatial determinants of local government action on climate change: an analysis of local authorities in England [PDF]
, 2014 The engagement of UK local authorities is vital if national government is to meet its climate change commitments. However, with no mandatory targets at local government level, other drivers must explain engagement. Using a Geographic Information System,
Mann, Sarah +2 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The approach of extracting features from the local environment for mobile robot [PDF]
, 2002 A new data fusion method to extract feathers from the local environment for mobile robot's navigation has been developed and implemented. This method, named the obstacle group, compresses data in a series of levels in order to reduce data quantity ...
Hong W(洪伟) +2 more
core +2 more sources
AtmosphereIn order to explore the variation law and causes of the humidity effect of local water bodies, this paper selects the data of encrypted automatic weather stations (encrypted stations) and national conventional meteorological stations (conventional ...
Kai Liu +3 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Managing indirect environmental impact within local authorities' standardized environmental management systems [PDF]
, 2007 Many local authorities use standardized environmental management systems (EMSs) to improve their environmental management. These authorities often find it difficult to manage environmental impact caused by their exercise of authority i.e.
Hjelm, Olof, +1 more
core +1 more source