Results 91 to 100 of about 8,025,626 (297)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Robust Feature Detection and Local Classification for Surfaces Based on Moment Analysis [PDF]
The stable local classification of discrete surfaces with respect to features such as edges and corners or concave and convex regions, respectively, is as quite difficult as well as indispensable for many surface processing applications.
Telea, Alexandru +8 more
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Local discriminant wavelet packet basis for texture classification [PDF]
Wavelet packets are well-known for their ability to compactly represent textures consiting of oscillatory patterns such as fingerprints or striped cloth.
Rajpoot, Nasir M. (Nasir Mahmood)
core
Bidirectional branch and bound for controlled variable selection. Part III: local average loss minimization [PDF]
The selection of controlled variables (CVs) from available measurements through exhaustive search is computationally forbidding for large-scale processes. We have recently proposed novel bidirectional branch and bound (B-3) approaches for CV selection
Kariwala, Vinay, Cao, Yi
core +1 more source
ML-Net: A Multi-Local Perception Network for Healthy and Bleached Coral Image Classification
Healthy coral reefs provide diverse habitats for marine life, playing a crucial role in marine ecosystems. Coral health is under threat due to global climate change, ocean pollution, and other environmental stressors, leading to coral bleaching.
Sai Wang +9 more
doaj +1 more source
Recognizing Objects in 3D Point Clouds with Multi-Scale Local Features
Recognizing 3D objects from point clouds in the presence of significant clutter and occlusion is a highly challenging task. In this paper, we present a coarse-to-fine 3D object recognition algorithm.
Min Lu +4 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
We present a technique to adapt the domain of local features through the matching process to augment their discriminative power. We start with local affine features selected and normalized independently in training and test images, and jointly expand their domain as part of the correspondence process, akin to a (non-rigid) registration task that yields
Vedaldi, A, Soatto, S
openaire +2 more sources

