Results 91 to 100 of about 7,238,657 (296)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Proposed face recognition system after plastic surgery

IET Computer Vision, 2016
Plastic surgery is considered as a challenging research issue in the field of face recognition. Nevertheless, it has yet to be studied from theoretical and experimental perspectives.
Amal Seralkhatem Osman Ali, Vijanth Sagayan, Aamir Malik, Azrina Aziz   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Sequential Complexity as a Descriptor for Musical Similarity [PDF]

, 2014
We propose string compressibility as a descriptor of temporal struc-ture in audio, for the purpose of determining musical similarity. Our descriptors are based on computing track-wise compression rates of quan-tised audio features, using multiple ...
Mauch, M, Peter Foster, Matthias Mauch, Simon Dixon, Foster, P, Dixon, S   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Optimal Linear Quadratic Feedback State Regulator Problem for Index One Descriptor Systems [PDF]

In this note we present both necessary and sufficient conditions for the existence of a linear static state feedback controller if the system is described by an index one descriptor system. A priori no definiteness restrictions are made w.r.t.
Salmah, Y., Wijayanti, I.E., Engwerda, J.C.   +2 more
core  

A feature selection framework for small sampling data in content-based image retrieval system [PDF]

, 2005
Content-based image retrieval (CBIR) systems have drawn interest from many researchers in recent years. Over the last few years, kernel-based approach has been a popular choice for the implementation of the relevance feedback based CBIR system.
Wong, K.W., Fung, C.C., Chung, K.P.
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A New Laws Filtered Local Binary Pattern Texture Descriptor for Ultrasound Kidney Images Retrieval

Applied Medical Informatics, 2014
Content Based Image Retrieval (CBIR) is an inevitable technique in medical applications. One of the important tasks in CBIR is the feature extraction process.
Chelladurai CALLINS CHRISTIYANA, Vayanaperumal RAJAMANI   +1 more
doaj