Results 121 to 130 of about 216,031 (287)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Numerical Analysis of Localized Electric Field Enhancement in Apertureless Near Field Optical Microscopy

open access: yesIEEE Photonics Journal
In this work, we investigate the effects of two distinct physical mechanisms, the antenna effect and plasmon resonance, on electric field enhancement in representative geometrical structures and at the apex of a sharp tip.
Ayushman Ramola   +4 more
doaj   +1 more source

Local field enhancement of an infinite conical metal tip illuminated by a focused beam [PDF]

open access: yes
We present a systematic numerical investigation of conical metal tips which are commonly used in tip-enhanced Raman spectroscopy (TERS). Different from previous studies, we focus on how the tip length and the illumination condition influence the local ...
Martin, Olivier J. F.   +2 more
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Nano-patterning photosensitive polymers using local field enhancement at the end of apertureless SNOM tips

open access: yes, 2003
International audienceWe show experimentally that local optical field enhancement can occur at the end of an apertureless SNOM tip illuminated by an external light source.
R. Bachelot   +9 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Local Field Asymmetry Drives Second-Harmonic Generation in Noncentrosymmetric Nanodimers

open access: yes, 2007
We demonstrate that second-harmonic generation (SHG) from arrays of noncentrosymmetric T-shaped gold nanodimers with a nanogap arises from asymmetry in the local fundamental field distribution and is not related strictly to nanogap size.
Hannu Husu (1690756)   +6 more
core   +1 more source

Integrating Patient‐Reported Quality Measures in Systemic Lupus Erythematosus: Development of the American College of Rheumatology Implementation Guide

open access: yesArthritis Care &Research, EarlyView.
Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcome measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semistructured interviews ...
Catherine Nasrallah   +13 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Home - About - Disclaimer - Privacy