Results 101 to 110 of about 1,201,861 (268)

Experimental Study of Saturated Flow Boiling Heat Transfer in an Array of Micro-pin-fins

Zhileng xuebao, 2018
Experiments were carried out to investigate the saturated flow boiling heat transfer and visualize the two-phase flow patterns for deionized water in a micro-pin-fin heat sink with cylindrical fins with a height of 500 μm and diameter of 500 μm. The test
李慧君, 郭保仓, 杜保周, 刘志刚, 吕明明   +4 more
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Effects of Near-Infrared Photobiomodulation on Local Skin Blood Flow in Healthy Subjects

Photonics
Photobiomodulation causes an immediate increase in local blood flow. This study aimed to investigate the effect of 890 nm NIR exposure on local skin blood flow in young and middle-aged healthy subjects. In this placebo-controlled clinical trial, 12 young
Misbah Riaz, Patrick Christian Bösch, Marte Kierulf Åm, Reinold Ellingsen, Dag Roar Hjelme, Sven Magnus Carlsen, Sverre Christian Christiansen   +6 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Study on the Mechanism of Local Scour Around Bridge Piers

Journal of Marine Science and Engineering
Local scour around bridge piers poses significant challenges to the stability and safety of bridge structures. Local scour results from the combined effects of increased longitudinal flow velocity, the direct impact of the flow in front of the pier, and ...
Haiyang Dong, Zongyu Li, Zhilin Sun
doaj   +1 more source

Numerical Study on Concrete Pumping Behavior via Local Flow Simulation with Discrete Element Method. [PDF]

Materials (Basel), 2019
Zhan Y, Gong J, Huang Y, Shi C, Zuo Z, Chen Y.   +5 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Exploring hydrological system performance for alpine low flows in local and continental prediction systems

Journal of Hydrology: Regional Studies
Study region: The European alpine space.Study focus: Despite the advancements in hydrological modeling, there is a lack of comparative studies quantifying the performance differences between local and large-scale models, particularly in the context of ...
Annie Y.-Y. Chang, Maria-Helena Ramos, Shaun Harrigan, Christel Prudhomme, François Tilmant, Daniela I.V. Domeisen, Massimiliano Zappa   +6 more
doaj   +1 more source