Results 81 to 90 of about 1,201,861 (268)

Two-Phase Bubble Columns: A Comprehensive Review

ChemEngineering, 2018
We present a comprehensive literature review on the two-phase bubble column; in this review we deeply analyze the flow regimes, the flow regime transitions, the local and global fluid dynamics parameters, and the mass transfer phenomena.
Giorgio Besagni, Fabio Inzoli, Thomas Ziegenhein   +2 more
doaj   +1 more source

Local Flow Matching Generative Models

IEEE Transactions on Information Theory
Flow Matching (FM) is a simulation-free method for learning a continuous, invertible flow that interpolates between two distributions, and in particular generates data from noise. Inspired by the variational nature of the diffusion process as a gradient flow, we introduce a stepwise FM model, Local Flow Matching (LFM), which sequentially learns a ...
Chen Xu, Xiuyuan Cheng, Yao Xie 0002
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Some Mathematical Examples of Emergent Intuitive Local Time Flow

Foundations
After reviewing important historical and present day ideas about the concept of time, we develop some instances of mathematical examples where, from the interaction of concepts that model interactions of things in the observable world, time flow emerges ...
Manuel L. Esquível, Nadezhda P. Krasii, Philippe L. Didier   +2 more
doaj   +1 more source

Local blood flow analysis and visualization from RGB-video sequences

Current Directions in Biomedical Engineering, 2019
The extraction of heart rate and other vital parameters from video recordings of a person has attracted much attention over the last years. In this paper, we examine time differences between distinct spatial regions using remote photoplethysmography ...
Kossack Benjamin, Wisotzky Eric L., Hilsmann Anna, Eisert Peter, Hänsch Ronny   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Experimental Study on the Effects of Flexible Vegetation on Hydraulic Characteristics and Local Head Losses of Overland Flow

工程科学与技术, 2013
:The series of overland flow experiments were conducted on flexible vegetative beds with 20 degree slopes,and the hydraulic characteristics of sheeted flows were observed for parameters such as surface velocity,flow depth,and the averaged velocity.The ...
王协康, 刘同宦, 叶龙, 易子靖, 黄尔, 刘兴年   +5 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source