Results 81 to 90 of about 3,532,475 (307)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Can Local Food Go Mainstream? [PDF]

Local Food, Relocalization, Supermarket, Distribution Center, Economies of Size, Transportation Efficiency, Food Consumption/Nutrition/Food Safety, Marketing,
DiGiacomo, Gigi, Gomez, Miguel I., King, Robert P.   +2 more
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Cultural Influence of Local Food Heritage on Sustainable Development

World
This article explores relations between cultural heritage and cultural values for sustainable development in the Enugu region. It discusses the potential to advance a cultural approach to sustainable development of regions by examining the cultural food ...
Gladys Ogochukwu Chukwurah, Francis Ogochukwu Okeke, Matthew Ogorchukwu Isimah, Evidence Chinedu Enoguanbhor, Foluso Charles Awe, Rosemary Chidimma Nnaemeka-Okeke, Shuang Guo, Ifeanyichukwu Valentine Nwafor, Chioma Angela Okeke   +8 more
doaj   +1 more source

Discussion [PDF]

, 2005
This report presents case studies of local initiatives that have overcome obstacles and successfully promoted local food. To start an initiative that is ecologically, economically and socially sustainable and combines organic food production with ...
Kakriainen, Salla, von Essen, Hans
core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Does social media involvement matter? A scoping review of memorable tourism experience on local food

Cogent Social Sciences
This research seeks to systematically investigates the role of social media in shaping memorable tourism experiences through local food. It evaluates previous studies in this area, highlights existing gaps and limitations, and proposes avenues for ...
Sartika, Andriani Kusumawati, Anni Rahimah, Yusri Abdillah   +3 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Local Food Systems: Concepts, Impacts, and Issues [PDF]

This comprehensive overview of local food systems explores alternative definitions of local food, estimates market size and reach, describes the characteristics of local consumers and producers, and examines early indications of the economic and health ...
Clark, Shellye, Da Pra, Michelle, Hand, Michael S., Lohr, Luanne, Low, Sarah A., Martinez, Stephen W., Newman, Constance, Pollack, Susan L., Ralston, Katherine L., Smith, Travis A., Vogel, Stephen J.   +10 more
core   +4 more sources

Demonstrasi Modifikasi Tepung Bayam Hijau (Tebayam Stipaba) Bahan Pangan Lokal untuk Menurunkan Hipertensi Lansia pada Kader Posyandu Lansia di Dusun Karya I

J.Abdimas
Background: Based on Demographic Survey data, Indonesia is currently entering the aging population phase, where the proportion of the elderly population is increasing. Hypertension is a common problem experienced by the elderly. The global target for non-
Sherly Angellina, Luluk Handayani, Lisnawati Lisnawati, Gloria Fortunata Bunga Elo   +3 more
doaj   +1 more source