Results 61 to 70 of about 9,643,925 (303)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Northeastern Chinese Sauerkraut Juice as a Water Replacer in Pork Fillings: Flavor Profiles and Sensory Attributes

Foods
In this study, the volatile organic compound (VOC) profiles and sensory quality of pork baozi fillings prepared with different substitution levels of Northeastern Chinese sauerkraut juice were characterized using an electronic nose, electronic tongue ...
Dezhuang Gong, Mengzhou Wang, Chunling Li, Zhitang Liang, Danshi Zhu   +4 more
doaj   +1 more source

Recognition and localization of food in cooking videos [PDF]

Proceedings of the Joint Workshop on Multimedia for Cooking and Eating Activities and Multimedia Assisted Dietary Management, 2018
In this paper, we describe experiments with techniques for locating foods and recognizing food states in cooking videos. We describe production of a new data set that provides annotated images for food types and food states. We compare results with two techniques for detecting food types and food states, and then show that recognizing type and state ...
Aboubakr, Nachwa, Ronfard, Rémi, Crowley, James L.   +2 more
openaire   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Local food system planning on multiple governance scales: a grounded theory analysis

Frontiers in Sustainable Food Systems
IntroductionLocal food systems (LFS) comprise the people, policies, infrastructure and practices of food production, distribution, and consumption in localized areas.
Jesse Decker Ure, Andrew J. South, Clifton B. Farnsworth   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Local Food Systems: Concepts, Impacts, and Issues [PDF]

This comprehensive overview of local food systems explores alternative definitions of local food, estimates market size and reach, describes the characteristics of local consumers and producers, and examines early indications of the economic and health ...
Vogel, Stephen J., Lohr, Luanne, Martinez, Stephen W., Clark, Shellye, Pollack, Susan L., Hand, Michael S., Low, Sarah A., Ralston, Katherine L., Smith, Travis A., Newman, Constance, Da Pra, Michelle   +10 more
core   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Differential Effects of Commercial Food-Grade Carrageenan Preparations on DSS-Induced Colitis and Gut Microbiota in Mice

Foods
Carrageenan (CGN) is widely used in processed foods and is typically supplied as a commercial preparation blended with other hydrocolloids to improve gelling properties, rather than as a single purified polymer.
Jiyu Nie, Danying Chen, Chengfeng Yu, Zengliang Jiang, Haibo Pan, Xingqian Ye, Shiguo Chen   +6 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source