Results 41 to 50 of about 9,268,341 (296)

One Place Doesn't Fit All: Improving the Effectiveness of Sustainability Standards by Accounting for Place

Frontiers in Sustainable Food Systems, 2020
The growing interest in incentivizing sustainable agricultural practices is supported by a large network of voluntary production standards, which aim to offer farmers and ranchers increased value for their product in support of reduced environmental ...
Kevin E. Jablonski, Jasmine A. Dillon, James W. Hale, Becca B. R. Jablonski, Michael S. Carolan   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Examining green purchasing. The role of environmental concerns, perceptions on climate change, preferences for EU integration, and media exposure

Frontiers in Environmental Science, 2023
Factors impacting green consumption studied in the literature include 1) economic incentives and possibilities, 2) socio-dem1ographic segmentation, 3) values, emotions and personal responsibilities, 4) information including education and mass media, 5 ...
Martin Hlaváček, Inna Čábelková, David Brož, Luboš Smutka, Petr Prochazka   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Local knowledge of using rangeland plants in the traditional dishes of the Lak tribe in the Dereshahr city, Ilam province [PDF]

Dānishhā-yi būmī-i Īrān
The erosion of traditional knowledge is a pressing global issue. This study aims to address this concern by investigating the traditional culinary practices of the Laki community in Darreh Shahr, Iran.
soheila yousofvand, mojgansadat azimi, Mojtaba jahantigh, Abolfazl Sharifiann   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Local Food Systems: Concepts, Impacts, and Issues [PDF]

This comprehensive overview of local food systems explores alternative definitions of local food, estimates market size and reach, describes the characteristics of local consumers and producers, and examines early indications of the economic and health ...
Vogel, Stephen J., Lohr, Luanne, Martinez, Stephen W., Clark, Shellye, Pollack, Susan L., Hand, Michael S., Low, Sarah A., Ralston, Katherine L., Smith, Travis A., Newman, Constance, Da Pra, Michelle   +10 more
core   +2 more sources

Is Local Food More Expensive? A Grand Rapids Case Study [PDF]

, 2012
Is locally produced food more expensive than non-locally produced food? As Americans become more aware of how their food is produced and where it is sourced, this question becomes more pertinent. This study compares prices for local fruits and vegetables,
Sauer, Christine
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source