Results 41 to 50 of about 946,364 (311)

Local Food, Food Democracy, and Food Hubs

Journal of Agriculture, Food Systems, and Community Development, 2015
In western North Carolina, where we and others have been working to build local food systems for the last 15 years, food hubs are part of an expanding network of local food distribution infrastructure intended to help the region's smaller local farms access larger, more mainstream market outlets.
Allison Perrett, Charlie Jackson
openaire   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Local knowledge of using rangeland plants in the traditional dishes of the Lak tribe in the Dereshahr city, Ilam province [PDF]

Dānishhā-yi būmī-i Īrān
The erosion of traditional knowledge is a pressing global issue. This study aims to address this concern by investigating the traditional culinary practices of the Laki community in Darreh Shahr, Iran.
soheila yousofvand, mojgansadat azimi, Mojtaba jahantigh, Abolfazl Sharifiann   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Food Security, Local Access to Healthy Foods, and Malnutrition [PDF]

Ecology of Food and Nutrition, 2021
Ecology of Food and Nutrition (EFN) promotes scholarly discussion and engagement on the holistic and cross-cultural dimensions of food and nutrition.
openaire   +2 more sources

The Local Food programme: A Social Return on Investment Approach. Final Report to The Royal Society of Wildlife Trusts [PDF]

, 2014
In March 2013, the University of Gloucestershire’s Countryside and Community Research Institute (CCRI) were commissioned to undertake an assessment of the Local Food programme using the Social Return on Investment (SROI) framework, an established ...
Courtney, Paul
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Exploring Interactions Between Arkansas Urban Producers: Social Networks and Modes of Information Seeking

Journal of Human Sciences and Extension, 2022
The purpose of this study was to explore the social networks and interactions between urban producers in Arkansas through a social network analysis.
Catherine E. Sanders, Don W. Edgar, Casandra K. Cox, Leslie D. Edgar   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source