Results 81 to 90 of about 6,699,757 (251)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Effect of local fractional derivatives on Riemann curvature tensor [PDF]
, 2022 In this short note, we investigate the effect of the local fractional derivatives on the Riemann curvature tensor that is a common tool in calculating curvature of a Riemannian manifold.
Aydin, Muhittin Evren
core +1 more source
New Approaches to Fractal–Fractional Bullen’s Inequalities Through Generalized Convexity
Fractal and FractionalThis paper introduces a new identity involving fractal–fractional integrals, which allow us to derive several new Bullen-type inequalities via generalized convexity.
Wedad Saleh +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Optimal control of fractional systems: a diffusive formulation [PDF]
, 2010 Optimal control of fractional linear systems on a finite horizon can be classically formulated using the adjoint system. But the adjoint of a causal fractional integral or derivative operator happens to be an anti-causal operator: hence, the adjoint ...
Matignon, Denis
core
On Local Weak Solutions for Fractional in Time SOBOLEV-Type Inequalities
Journal of Function Spaces, 2020 We consider two fractional in time nonlinear Sobolev-type inequalities involving potential terms, where the fractional derivatives are defined in the sense of Caputo.
Mohaemd Jleli, Bessem Samet
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Pricing the Weather Derivatives in the Presence of Long Memory in Temperatures [PDF]
Weather derivatives are financial contracts for which the underlying is not a traded asset. Therefore, they cannot be priced by the traditional financial theory based on the hedging portfolio and on the arbitrage-free argument.
Hélène Hamisultane
core
Fractional robust control of ligthly damped systems [PDF]
, 2006 The article proposes a method to design a robust controller ensuring the damping ratio of a closed-loop control. The method uses a contour para-meterized by the damping ratio in the Nichols plane and the complex non-integer (or fractional)differentiation
Janat, Yaman +3 more
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source