Results 81 to 90 of about 6,121,976 (240)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Generalized Pompeiu type inequalities for local fractional integrals and its applications
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Erden, Samet +2 more
openaire +1 more source
Necessary optimality conditions for fractional action-like problems with intrinsic and observer times [PDF]
We prove higher-order Euler-Lagrange and DuBois-Reymond stationary conditions to fractional action-like variational problems.
Frederico, G.S.F., Torres, D.F.M.
core +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Efficient solution of a wave equation with fractional-order dissipative terms [PDF]
We consider a wave equation with fractional-order dissipative terms modeling viscothermal losses on the lateral walls of a duct, namely the Webster-Lokshin model.
Haddar, Houssem +6 more
core +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Fractional robust control of ligthly damped systems [PDF]
The article proposes a method to design a robust controller ensuring the damping ratio of a closed-loop control. The method uses a contour para-meterized by the damping ratio in the Nichols plane and the complex non-integer (or fractional)differentiation
Janat, Yaman +3 more
core
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Fractional integrals on compact Riemannian symmetric spaces of rank one
In this paper we study mixed norm boundedness for fractional integrals related to Laplace-Beltrami operators on compact Riemannian symmetric spaces of rank one.
Ciaurri, Óscar [0000-0002-1695-3311] +2 more
core +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

