Results 61 to 70 of about 6,121,976 (240)

On fractional deviation operators

open access: yesLe Matematiche, 1997
The so called fractional deviation operators are introduced. This class of integral transforms appears naturally from the study of iteration of fractional integrals of Riemann-Liouville type. Since B.
Carlos C. Peña
doaj  

Double Local Fractional Yang–Laplace Transform for Local Fractional PDEs on Fractal Domains

open access: yesFractal and Fractional
This study introduces a novel analytical technique known as the double local fractional Yang–Laplace transform method (LFLζ2) and rigorously investigates its foundational properties, including linearity, differentiation, and convolution.
Djelloul Ziane   +3 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Hermite–Hadamard- and Pachpatte-type integral inequalities for generalized subadditive functions in the fractal sense

open access: yesMiskolc Mathematical Notes
In this paper, we establish the generalized Hermite–Hadamard- and Pachpatte-type integral inequalities for local fractional integrals via the generalized subadditive functions.
Tingsong Du, Lei Xu
doaj   +1 more source

Local discontinuous Galerkin method for the integral fractional Laplacian

open access: yesCoRR
We develop and analyze a local discontinuous Galerkin (LDG) method for solving integral fractional Laplacian problems on bounded Lipschitz domains. The method is based on a three-field mixed formulation involving the primal variable, its gradient, and the corresponding Riesz potential, yielding a flux-based structure well suited for LDG discretizations
Rubing Han, Shuonan Wu, Hao Zhou
openaire   +3 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Some Generalized Inequalities Involving Local Fractional Integrals and their Applications for Random Variables and Numerical Integration [PDF]

open access: yesJournal of Applied Mathematics, Statistics and Informatics, 2016
AbstractWe establish generalized pre-Grüss inequality for local fractional integrals. Then, we obtain some inequalities involving generalized expectation,p−moment, variance and cumulative distribution function of random variable whose probability density function is bounded.
Erden, Samet   +3 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy