Results 51 to 60 of about 10,416 (247)
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
A New Approach for Solving System of Local Fractional Partial Differential Equations [PDF]
, 2016 In this paper, we apply a new method for solving system of partial differential equations within local fractional derivative operators. The approximate analytical solutions are obtained by using the local fractional Laplace variational iteration method ...
Jafari, Hossein, Jassim, Hassan K.
core +1 more source
, 2017 By using the penalization method and the Ljusternik-Schnirelmann theory, we investigate the multiplicity of positive solutions of the following fractional Schr\"odinger equation $$ \e^{2s}(-\Delta)^{s} u + V(x)u = f(u) \mbox{ in } \mathbb{R}^{N} $$ where
Ambrosio, Vincenzo
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
On the solution of two-dimensional local fractional LWR model of fractal vehicular traffic flow [PDF]
Mathematics and Computational SciencesThis study proposed a two-dimensional local fractional Lighthill-Whitham-Richards (LWR) model of fractal vehicular traffic flow. The non-differentiable traffic parameters that arise in traffic flow are addressed by this model.
Pranay Goswami +2 more
doaj +1 more source
Journal of Nonlinear Sciences and Applications, 2016 Summary: In this article, a coupling of the variational iteration method with the Sumudu transform via the local fractional calculus operator is proposed for the first time. As a testing example, the exact solution for the local fractional diffusion equation in fractal one-dimensional space is obtained.
Gao, Feng +3 more
openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Multigrid Methods for Space Fractional Partial Differential Equations
, 2015 We propose some multigrid methods for solving the algebraic systems resulting from finite element approximations of space fractional partial differential equations (SFPDEs).
Jiang, Yingjun, Xu, Xuejun
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source