Results 41 to 50 of about 2,273,193 (314)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Empirical potential function for simplified protein models: Combining contact and local sequence-structure descriptors

open access: yes, 2006
An effective potential function is critical for protein structure prediction and folding simulation. Simplified protein models such as those requiring only C-alpha or backbone atoms are attractive because they enable efficient search of the ...
Liang, J, Chen, R, Zhang, J
core   +1 more source

Generalized Local Operators Between Function Modules

open access: yesپژوهش‌های ریاضی, 2021
Let X be a compact Hausdorff space, E be a normed space, A(X,E)  be a regular Banach function algebra on X , and A(X,E) be a subspace of C(X,E) . In this paper, first we introduce the notion of localness of an additive map S:A(X,E) → C(X,E) with respect ...
Fereshteh Sady, Masoumeh Najafi Tavani
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A localization inequality for set functions

open access: yesJournal of Combinatorial Theory, Series A, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
László Lovász 0001, Michael E. Saks
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Characterizations of Hayashi-Samuel Spaces via Boundary Points

open access: yesCommunications in Advanced Mathematical Sciences, 2019
Some new closure operators in topological spaces with ideals are a part of this paper. A comparative study of a new type of boundary point, which is defined  with the help of the local function and the boundary points will be discussed through this paper.
Shyamapada Modak   +2 more
doaj  

Multidisciplinary management of a norovirus outbreak in Tuscany, Italy

open access: yesItalian Journal of Food Safety
Norovirus (NoV) is one of the most frequent agents responsible for foodborne outbreaks. Transmission occurs through the consumption of contaminated food or water or via contact with contaminated surfaces.
Clara Girardi   +14 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Improving the reliability of functional localizers

open access: yesNeuroImage, 2011
A critical assumption underlying the practice of functional localization is that the voxels identified by functional localization are essentially the same as those activated in the main experiment for a particular anatomical area. Violations of this assumption bias the resulting analyses and can dramatically increase the likelihood of both Type I and ...
Keith J. Kawabata Duncan   +1 more
openaire   +2 more sources

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