Results 51 to 60 of about 2,273,193 (314)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Local function versus local closure function in ideal topological spaces
, 2016 The aim of this paper is to further investigate properties of the local closure function, as a generalization of the ?-closure and the local function in ideal topological spaces. Similarities and differences between it and the local function are
Aleksandar Pavlovic
core +1 more source
NEW SUPRA TOPOLOGIES FROM OLD VIA IDEALS
Journal of New Theory, 2015 In this paper, we define a supra topology obtained as an associated structure on a supratopological space (X, τ ) induced by an ideal on X.
Ali Kandil +3 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Local structure studies using the pair distribution function
EPJ Web of Conferences, 2015 The pair distribution analysis method is a fast spreading structural analysis method allowing to go beyond classical crystallographic analysis by providing quantitative information about local as well as meso-structure.
Bordet Pierre
doaj +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Local government scrutiny and governance: Limits and possibilities [PDF]
, 2007 The central focus of this thesis is the role of scrutiny within the modernised system of local government and governance. The study was carried out from an insider-research perspective within the scrutiny team of a unitary authority. The scrutiny process
Wistow, Jonathan
core
Electrical stimulation for brighter persistent luminescence
Light: Science & ApplicationsAn immature understanding of the mechanisms of persistent luminescence (PersL) has hindered the development of new persistent luminescent materials (PersLMs) with increased brightness.
Xilin Ma, Yuhua Wang, Takatoshi Seto
doaj +1 more source
Local polynomial method for frequency response function identification
Systems Science & Control Engineering, 2020 Here we propose the local polynomial method to solve the problem of estimating the frequency response function in the linear system. Compared with other nonparametric identification methods based on the windowing strategies, this new identification ...
Dong Xiguang +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source