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Complete issue of Issue 7, 2010 (3MB).
Daniel Grafton
doaj +1 more source
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Financing local government in Hungary [PDF]
Hungary has undertaken a bold and far-ranging reform of its system of subnational finances. This paper outlines the changes introduced in the system of local finance as a result of the 1990 Local Self-Government Act, and the 1990 Act on Local Taxes and ...
Bird, Richard, Wallich, Christine
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Focus on Outcomes: Redesigning Minnesota's Local Government Services [PDF]
Today Minnesota is facing a "new normal" -- with an increasingly aging population, growing public service needs, a changing workforce and a shrinking base of taxpayers -- and these circumstances require new innovations. In November 2011, more than 400 of
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Complete Issue: No.4 November 2009 (2.2MB)
Complete issue of No. 4 November 2009 (2.2MB).
Anna Vo
doaj +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Environmental resource crises involving farmers and herdsmen in developing nations can affect the realisation of the United Nations 2030 Sustainable Development Goals’(SDGs) targets, such as elimination of poverty, elimination of hunger and food ...
Samuel Okafor +6 more
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Resource capability for local government in mainstreaming gender into disaster risk reduction: evidence from Indonesia [PDF]
Understanding how local government responds to gender vulnerability and gender capacity is important to make cities safer both for women and for men.
Amaratunga, Dilanthi, Yumarni, Tri
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