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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Post-Disaster Road Reconstruction in Aceh - Local Governments’ Role in Road Maintenance [PDF]
Many studies have shown the importance of improved road infrastructure towards economic development of a region through economic agglomeration and widened business network coverage resulting from better access and higher mobility. However, such benefit
Amaratunga, Dilanthi, Hayat, Ezri
core +3 more sources
Metropolises - the Contemporary Challenge to Local Governments
Metropolisation is a process that includes the consequences of global phenomena transferred to the level of metropolitan areas, being the result of various legal and social processes, which is best illustrated by the example of French and Polish ...
Monika Augustyniak
doaj +1 more source
Governance and Sustainability in Local Government
According to auditor reports in 2021, local government councils are failing their communities and their voters. Victorian Auditor General’s Office (VAGO) Reports 2021 suggest that the Councils of local governments are rife with conflicts of interest, manipulation of land deals, lacking independence and captured by their CEOs.
Armstrong, Anona, Li, Yongqiang
openaire +2 more sources
A comparative study of local governments in the constitutions of selected EU countries and Turkey
In the effort to examine local governments within a country, the first place to look at would be the constitution of that state. Constitutions usually provide us with important information about local governments; on their types, competencies, revenues ...
core +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Of the numerous applications of GIS, administration and public services count among the main fields of application. They are both the users and the owners of the largest amount of spatial data.
Medolińska Katarzyna +2 more
doaj +1 more source
Local self-government or local co-governance?
The article discusses “local self-government”, a core concept in a charter of the Council of Europe, and departs from a debate in the Norwegian Parliament about constitutional protection of local self-government. Newly, such a change was voted down, and this serves as an opportunity to question the idea about local self-government in a time when there ...
openaire +3 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

