Results 91 to 100 of about 7,930,152 (319)

Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment

Frontiers in Oncology, 2018
While treatment with surgery, radiotherapy and/or chemotherapy may prolong life for patients with glioblastoma, recurrence is inevitable. What is still being discovered is how much these treatments and recurrence of disease affect the molecular profiles ...
Amanda L. Hudson, Amanda L. Hudson, Amanda L. Hudson, Nicole R. Parker, Nicole R. Parker, Nicole R. Parker, Peter Khong, Peter Khong, Peter Khong, Jonathon F. Parkinson, Jonathon F. Parkinson, Jonathon F. Parkinson, Trisha Dwight, Trisha Dwight, Trisha Dwight, Rowan J. Ikin, Rowan J. Ikin, Rowan J. Ikin, Ying Zhu, Ying Zhu, Ying Zhu, Jason Chen, Helen R. Wheeler, Helen R. Wheeler, Helen R. Wheeler, Viive M. Howell, Viive M. Howell, Viive M. Howell   +27 more
doaj   +1 more source

Opportunities and challeges of tourist valorization of Zambratija cove (Umag) [PDF]

Studia Universitatis Hereditati, 2017
The area surrounding Zambratija Cove has been representing a unique destination for researchers due to its archaeological treasures. In 2008 new archaeological findings were discovered, which, as a result of its uniqueness, can be classified at the very
Ida Koncani Uhač, Neven Iveša, Danijela Mioković, Ana Žužić   +3 more
doaj   +1 more source

Lefschetz for Local Picard groups [PDF]

Annales scientifiques de l'École normale supérieure, 2014
We prove a strengthening of the Grothendieck-Lefschetz hyperplane theorem for local Picard groups conjectured by Koll r. Our approach, which relies on acyclicity results for absolute integral closures, also leads to a restriction theorem for higher rank bundles on projective varieties in positive characteristic.
Aise Johan de Jong, Bhargav Bhatt
openaire   +3 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

The Local Group

, 2000
Invited review to appear in the proceedings of "Microlensing 2000: A New Era of Microlensing Astrophysics", Cape Town, South Africa, ASP Conf. Ser., eds. J.W. Menzies and P.D. Sackett; 17 pages, 1 figure.
openaire   +2 more sources

Renegade subhaloes in the Local Group [PDF]

Monthly Notices of the Royal Astronomical Society: Letters, 2011
Abstract Using a dark matter only Constrained Local UniversE Simulation (CLUES) we examine the existence of subhaloes that change their affiliation from one of the two prominent hosts in the Local Group (i.e. the Milky Way and the Andromeda galaxy) to the other, and call these objects ‘renegade subhaloes’.
Stefan Gottlöber, Yehuda Hoffman, Noam I. Libeskind, Alexander Knebe, Gustavo Yepes, Timur Doumler, Timur Doumler   +6 more
openaire   +5 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Local description of phylogenetic group-based models [PDF]

, 2013
Motivated by phylogenetics, our aim is to obtain a system of equations that define a phylogenetic variety on an open set containing the biologically meaningful points. In this paper we consider phylogenetic varieties defined via group-based models.
Casanellas, Marta, Fernández-Sánchez, Jesús, Michałek, Mateusz   +2 more
core   +2 more sources

Densely locally minimal groups [PDF]

Topology and its Applications, 2019
We study locally compact groups having all dense subgroups (locally) minimal. We call such groups densely (locally) minimal. In 1972 Prodanov proved that the infinite compact abelian groups having all subgroups minimal are precisely the groups $\mathbb Z_p$ of $p$-adic integers. In [31], we extended Prodanov's theorem to the non-abelian case at several
Xi, W., Dikranjan, D., Shlossberg, M., Toller, D.   +3 more
openaire   +4 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source